Deciphering the Genetic Architecture of Plant Virus Resistance by GWAS, State of the Art and Potential Advances

Growing virus resistant varieties is a highly effective means to avoid yield loss due to infection by many types of virus. The challenge is to be able to detect resistance donors within plant species diversity and then quickly introduce alleles conferring resistance into elite genetic backgrounds. U...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Severine Monnot, Henri Desaint, Tristan Mary-Huard, Laurence Moreau, Valerie Schurdi-Levraud, Nathalie Boissot
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	plant virus GWAS Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/aded7b2df8004584b582450fbcec9bfa
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:aded7b2df8004584b582450fbcec9bfa
record_format	dspace
spelling	oai:doaj.org-article:aded7b2df8004584b582450fbcec9bfa2021-11-25T17:11:18ZDeciphering the Genetic Architecture of Plant Virus Resistance by GWAS, State of the Art and Potential Advances10.3390/cells101130802073-4409https://doaj.org/article/aded7b2df8004584b582450fbcec9bfa2021-11-01T00:00:00Zhttps://www.mdpi.com/2073-4409/10/11/3080https://doaj.org/toc/2073-4409Growing virus resistant varieties is a highly effective means to avoid yield loss due to infection by many types of virus. The challenge is to be able to detect resistance donors within plant species diversity and then quickly introduce alleles conferring resistance into elite genetic backgrounds. Until now, mainly monogenic forms of resistance with major effects have been introduced in crops. Polygenic resistance is harder to map and introduce in susceptible genetic backgrounds, but it is likely more durable. Genome wide association studies (GWAS) offer an opportunity to accelerate mapping of both monogenic and polygenic resistance, but have seldom been implemented and described in the plant–virus interaction context. Yet, all of the 48 plant–virus GWAS published so far have successfully mapped QTLs involved in plant virus resistance. In this review, we analyzed general and specific GWAS issues regarding plant virus resistance. We have identified and described several key steps throughout the GWAS pipeline, from diversity panel assembly to GWAS result analyses. Based on the 48 published articles, we analyzed the impact of each key step on the GWAS power and showcase several GWAS methods tailored to all types of viruses.Severine MonnotHenri DesaintTristan Mary-HuardLaurence MoreauValerie Schurdi-LevraudNathalie BoissotMDPI AGarticleplantvirusGWASBiology (General)QH301-705.5ENCells, Vol 10, Iss 3080, p 3080 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	plant virus GWAS Biology (General) QH301-705.5
spellingShingle	plant virus GWAS Biology (General) QH301-705.5 Severine Monnot Henri Desaint Tristan Mary-Huard Laurence Moreau Valerie Schurdi-Levraud Nathalie Boissot Deciphering the Genetic Architecture of Plant Virus Resistance by GWAS, State of the Art and Potential Advances
description	Growing virus resistant varieties is a highly effective means to avoid yield loss due to infection by many types of virus. The challenge is to be able to detect resistance donors within plant species diversity and then quickly introduce alleles conferring resistance into elite genetic backgrounds. Until now, mainly monogenic forms of resistance with major effects have been introduced in crops. Polygenic resistance is harder to map and introduce in susceptible genetic backgrounds, but it is likely more durable. Genome wide association studies (GWAS) offer an opportunity to accelerate mapping of both monogenic and polygenic resistance, but have seldom been implemented and described in the plant–virus interaction context. Yet, all of the 48 plant–virus GWAS published so far have successfully mapped QTLs involved in plant virus resistance. In this review, we analyzed general and specific GWAS issues regarding plant virus resistance. We have identified and described several key steps throughout the GWAS pipeline, from diversity panel assembly to GWAS result analyses. Based on the 48 published articles, we analyzed the impact of each key step on the GWAS power and showcase several GWAS methods tailored to all types of viruses.
format	article
author	Severine Monnot Henri Desaint Tristan Mary-Huard Laurence Moreau Valerie Schurdi-Levraud Nathalie Boissot
author_facet	Severine Monnot Henri Desaint Tristan Mary-Huard Laurence Moreau Valerie Schurdi-Levraud Nathalie Boissot
author_sort	Severine Monnot
title	Deciphering the Genetic Architecture of Plant Virus Resistance by GWAS, State of the Art and Potential Advances
title_short	Deciphering the Genetic Architecture of Plant Virus Resistance by GWAS, State of the Art and Potential Advances
title_full	Deciphering the Genetic Architecture of Plant Virus Resistance by GWAS, State of the Art and Potential Advances
title_fullStr	Deciphering the Genetic Architecture of Plant Virus Resistance by GWAS, State of the Art and Potential Advances
title_full_unstemmed	Deciphering the Genetic Architecture of Plant Virus Resistance by GWAS, State of the Art and Potential Advances
title_sort	deciphering the genetic architecture of plant virus resistance by gwas, state of the art and potential advances
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/aded7b2df8004584b582450fbcec9bfa
work_keys_str_mv	AT severinemonnot decipheringthegeneticarchitectureofplantvirusresistancebygwasstateoftheartandpotentialadvances AT henridesaint decipheringthegeneticarchitectureofplantvirusresistancebygwasstateoftheartandpotentialadvances AT tristanmaryhuard decipheringthegeneticarchitectureofplantvirusresistancebygwasstateoftheartandpotentialadvances AT laurencemoreau decipheringthegeneticarchitectureofplantvirusresistancebygwasstateoftheartandpotentialadvances AT valerieschurdilevraud decipheringthegeneticarchitectureofplantvirusresistancebygwasstateoftheartandpotentialadvances AT nathalieboissot decipheringthegeneticarchitectureofplantvirusresistancebygwasstateoftheartandpotentialadvances
_version_	1718412671589548032

Deciphering the Genetic Architecture of Plant Virus Resistance by GWAS, State of the Art and Potential Advances

Ejemplares similares