Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer
Altered protein glycosylation is increasingly recognized as a hallmark of cancer. Here, the authors profile the glycoproteome of 119 high-grade serous ovarian carcinoma tissues, showing that glycosylation patterns correlate with tumor molecular subtypes and clinical outcomes.
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Nature Portfolio
2020
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oai:doaj.org-article:adefa38328f3402b8173eaf99adced3f2021-12-02T14:41:15ZGlycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer10.1038/s41467-020-19976-32041-1723https://doaj.org/article/adefa38328f3402b8173eaf99adced3f2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19976-3https://doaj.org/toc/2041-1723Altered protein glycosylation is increasingly recognized as a hallmark of cancer. Here, the authors profile the glycoproteome of 119 high-grade serous ovarian carcinoma tissues, showing that glycosylation patterns correlate with tumor molecular subtypes and clinical outcomes.Jianbo PanYingwei HuShisheng SunLijun ChenMichael SchnaubeltDavid ClarkMinghui AoZhen ZhangDaniel ChanJiang QianHui ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
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Science Q Jianbo Pan Yingwei Hu Shisheng Sun Lijun Chen Michael Schnaubelt David Clark Minghui Ao Zhen Zhang Daniel Chan Jiang Qian Hui Zhang Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer |
description |
Altered protein glycosylation is increasingly recognized as a hallmark of cancer. Here, the authors profile the glycoproteome of 119 high-grade serous ovarian carcinoma tissues, showing that glycosylation patterns correlate with tumor molecular subtypes and clinical outcomes. |
format |
article |
author |
Jianbo Pan Yingwei Hu Shisheng Sun Lijun Chen Michael Schnaubelt David Clark Minghui Ao Zhen Zhang Daniel Chan Jiang Qian Hui Zhang |
author_facet |
Jianbo Pan Yingwei Hu Shisheng Sun Lijun Chen Michael Schnaubelt David Clark Minghui Ao Zhen Zhang Daniel Chan Jiang Qian Hui Zhang |
author_sort |
Jianbo Pan |
title |
Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer |
title_short |
Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer |
title_full |
Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer |
title_fullStr |
Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer |
title_full_unstemmed |
Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer |
title_sort |
glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/adefa38328f3402b8173eaf99adced3f |
work_keys_str_mv |
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