Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer

Altered protein glycosylation is increasingly recognized as a hallmark of cancer. Here, the authors profile the glycoproteome of 119 high-grade serous ovarian carcinoma tissues, showing that glycosylation patterns correlate with tumor molecular subtypes and clinical outcomes.

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Autores principales: Jianbo Pan, Yingwei Hu, Shisheng Sun, Lijun Chen, Michael Schnaubelt, David Clark, Minghui Ao, Zhen Zhang, Daniel Chan, Jiang Qian, Hui Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/adefa38328f3402b8173eaf99adced3f
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spelling oai:doaj.org-article:adefa38328f3402b8173eaf99adced3f2021-12-02T14:41:15ZGlycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer10.1038/s41467-020-19976-32041-1723https://doaj.org/article/adefa38328f3402b8173eaf99adced3f2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19976-3https://doaj.org/toc/2041-1723Altered protein glycosylation is increasingly recognized as a hallmark of cancer. Here, the authors profile the glycoproteome of 119 high-grade serous ovarian carcinoma tissues, showing that glycosylation patterns correlate with tumor molecular subtypes and clinical outcomes.Jianbo PanYingwei HuShisheng SunLijun ChenMichael SchnaubeltDavid ClarkMinghui AoZhen ZhangDaniel ChanJiang QianHui ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jianbo Pan
Yingwei Hu
Shisheng Sun
Lijun Chen
Michael Schnaubelt
David Clark
Minghui Ao
Zhen Zhang
Daniel Chan
Jiang Qian
Hui Zhang
Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer
description Altered protein glycosylation is increasingly recognized as a hallmark of cancer. Here, the authors profile the glycoproteome of 119 high-grade serous ovarian carcinoma tissues, showing that glycosylation patterns correlate with tumor molecular subtypes and clinical outcomes.
format article
author Jianbo Pan
Yingwei Hu
Shisheng Sun
Lijun Chen
Michael Schnaubelt
David Clark
Minghui Ao
Zhen Zhang
Daniel Chan
Jiang Qian
Hui Zhang
author_facet Jianbo Pan
Yingwei Hu
Shisheng Sun
Lijun Chen
Michael Schnaubelt
David Clark
Minghui Ao
Zhen Zhang
Daniel Chan
Jiang Qian
Hui Zhang
author_sort Jianbo Pan
title Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer
title_short Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer
title_full Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer
title_fullStr Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer
title_full_unstemmed Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer
title_sort glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/adefa38328f3402b8173eaf99adced3f
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