Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice

Mutational signatures induced by ionising radiation remain largely unexplored. Here in TP53 mutant mice, the authors characterise the genomic landscape of tumours induced by high- and low-energy radiation.

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Autores principales: Yun Rose Li, Kyle D. Halliwill, Cassandra J. Adams, Vivek Iyer, Laura Riva, Rashid Mamunur, Kuang-Yu Jen, Reyno del Rosario, Erik Fredlund, Gillian Hirst, Ludmil B. Alexandrov, David Adams, Allan Balmain
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/adf081533e9d46c2b04cbf253b8a5fd4
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spelling oai:doaj.org-article:adf081533e9d46c2b04cbf253b8a5fd42021-12-02T14:41:23ZMutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice10.1038/s41467-019-14261-42041-1723https://doaj.org/article/adf081533e9d46c2b04cbf253b8a5fd42020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14261-4https://doaj.org/toc/2041-1723Mutational signatures induced by ionising radiation remain largely unexplored. Here in TP53 mutant mice, the authors characterise the genomic landscape of tumours induced by high- and low-energy radiation.Yun Rose LiKyle D. HalliwillCassandra J. AdamsVivek IyerLaura RivaRashid MamunurKuang-Yu JenReyno del RosarioErik FredlundGillian HirstLudmil B. AlexandrovDavid AdamsAllan BalmainNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yun Rose Li
Kyle D. Halliwill
Cassandra J. Adams
Vivek Iyer
Laura Riva
Rashid Mamunur
Kuang-Yu Jen
Reyno del Rosario
Erik Fredlund
Gillian Hirst
Ludmil B. Alexandrov
David Adams
Allan Balmain
Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice
description Mutational signatures induced by ionising radiation remain largely unexplored. Here in TP53 mutant mice, the authors characterise the genomic landscape of tumours induced by high- and low-energy radiation.
format article
author Yun Rose Li
Kyle D. Halliwill
Cassandra J. Adams
Vivek Iyer
Laura Riva
Rashid Mamunur
Kuang-Yu Jen
Reyno del Rosario
Erik Fredlund
Gillian Hirst
Ludmil B. Alexandrov
David Adams
Allan Balmain
author_facet Yun Rose Li
Kyle D. Halliwill
Cassandra J. Adams
Vivek Iyer
Laura Riva
Rashid Mamunur
Kuang-Yu Jen
Reyno del Rosario
Erik Fredlund
Gillian Hirst
Ludmil B. Alexandrov
David Adams
Allan Balmain
author_sort Yun Rose Li
title Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice
title_short Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice
title_full Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice
title_fullStr Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice
title_full_unstemmed Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice
title_sort mutational signatures in tumours induced by high and low energy radiation in trp53 deficient mice
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/adf081533e9d46c2b04cbf253b8a5fd4
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