Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice
Mutational signatures induced by ionising radiation remain largely unexplored. Here in TP53 mutant mice, the authors characterise the genomic landscape of tumours induced by high- and low-energy radiation.
Guardado en:
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/adf081533e9d46c2b04cbf253b8a5fd4 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:adf081533e9d46c2b04cbf253b8a5fd4 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:adf081533e9d46c2b04cbf253b8a5fd42021-12-02T14:41:23ZMutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice10.1038/s41467-019-14261-42041-1723https://doaj.org/article/adf081533e9d46c2b04cbf253b8a5fd42020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14261-4https://doaj.org/toc/2041-1723Mutational signatures induced by ionising radiation remain largely unexplored. Here in TP53 mutant mice, the authors characterise the genomic landscape of tumours induced by high- and low-energy radiation.Yun Rose LiKyle D. HalliwillCassandra J. AdamsVivek IyerLaura RivaRashid MamunurKuang-Yu JenReyno del RosarioErik FredlundGillian HirstLudmil B. AlexandrovDavid AdamsAllan BalmainNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Yun Rose Li Kyle D. Halliwill Cassandra J. Adams Vivek Iyer Laura Riva Rashid Mamunur Kuang-Yu Jen Reyno del Rosario Erik Fredlund Gillian Hirst Ludmil B. Alexandrov David Adams Allan Balmain Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice |
description |
Mutational signatures induced by ionising radiation remain largely unexplored. Here in TP53 mutant mice, the authors characterise the genomic landscape of tumours induced by high- and low-energy radiation. |
format |
article |
author |
Yun Rose Li Kyle D. Halliwill Cassandra J. Adams Vivek Iyer Laura Riva Rashid Mamunur Kuang-Yu Jen Reyno del Rosario Erik Fredlund Gillian Hirst Ludmil B. Alexandrov David Adams Allan Balmain |
author_facet |
Yun Rose Li Kyle D. Halliwill Cassandra J. Adams Vivek Iyer Laura Riva Rashid Mamunur Kuang-Yu Jen Reyno del Rosario Erik Fredlund Gillian Hirst Ludmil B. Alexandrov David Adams Allan Balmain |
author_sort |
Yun Rose Li |
title |
Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice |
title_short |
Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice |
title_full |
Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice |
title_fullStr |
Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice |
title_full_unstemmed |
Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice |
title_sort |
mutational signatures in tumours induced by high and low energy radiation in trp53 deficient mice |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/adf081533e9d46c2b04cbf253b8a5fd4 |
work_keys_str_mv |
AT yunroseli mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT kyledhalliwill mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT cassandrajadams mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT vivekiyer mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT laurariva mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT rashidmamunur mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT kuangyujen mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT reynodelrosario mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT erikfredlund mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT gillianhirst mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT ludmilbalexandrov mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT davidadams mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice AT allanbalmain mutationalsignaturesintumoursinducedbyhighandlowenergyradiationintrp53deficientmice |
_version_ |
1718389891084058624 |