Accurate, scalable and integrative haplotype estimation

Haplotype information inferred by phasing is useful in genetic and genomic analysis. Here, the authors develop SHAPEIT4, a phasing method that exhibits sub-linear running time, provides accurate haplotypes and enables integration of external phasing information.

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Autores principales:	Olivier Delaneau, Jean-François Zagury, Matthew R. Robinson, Jonathan L. Marchini, Emmanouil T. Dermitzakis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/adf38d241b124818a2dec135ef6a75e5
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spelling	oai:doaj.org-article:adf38d241b124818a2dec135ef6a75e52021-12-02T16:57:45ZAccurate, scalable and integrative haplotype estimation10.1038/s41467-019-13225-y2041-1723https://doaj.org/article/adf38d241b124818a2dec135ef6a75e52019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13225-yhttps://doaj.org/toc/2041-1723Haplotype information inferred by phasing is useful in genetic and genomic analysis. Here, the authors develop SHAPEIT4, a phasing method that exhibits sub-linear running time, provides accurate haplotypes and enables integration of external phasing information.Olivier DelaneauJean-François ZaguryMatthew R. RobinsonJonathan L. MarchiniEmmanouil T. DermitzakisNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Olivier Delaneau Jean-François Zagury Matthew R. Robinson Jonathan L. Marchini Emmanouil T. Dermitzakis Accurate, scalable and integrative haplotype estimation
description	Haplotype information inferred by phasing is useful in genetic and genomic analysis. Here, the authors develop SHAPEIT4, a phasing method that exhibits sub-linear running time, provides accurate haplotypes and enables integration of external phasing information.
format	article
author	Olivier Delaneau Jean-François Zagury Matthew R. Robinson Jonathan L. Marchini Emmanouil T. Dermitzakis
author_facet	Olivier Delaneau Jean-François Zagury Matthew R. Robinson Jonathan L. Marchini Emmanouil T. Dermitzakis
author_sort	Olivier Delaneau
title	Accurate, scalable and integrative haplotype estimation
title_short	Accurate, scalable and integrative haplotype estimation
title_full	Accurate, scalable and integrative haplotype estimation
title_fullStr	Accurate, scalable and integrative haplotype estimation
title_full_unstemmed	Accurate, scalable and integrative haplotype estimation
title_sort	accurate, scalable and integrative haplotype estimation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/adf38d241b124818a2dec135ef6a75e5
work_keys_str_mv	AT olivierdelaneau accuratescalableandintegrativehaplotypeestimation AT jeanfrancoiszagury accuratescalableandintegrativehaplotypeestimation AT matthewrrobinson accuratescalableandintegrativehaplotypeestimation AT jonathanlmarchini accuratescalableandintegrativehaplotypeestimation AT emmanouiltdermitzakis accuratescalableandintegrativehaplotypeestimation
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Accurate, scalable and integrative haplotype estimation

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