Real-world evaluation of costs of illness for pneumonia in adult patients in Dubai-A claims database study.

<h4>Background</h4>Pneumonia is a significant cause of morbidity and mortality among adults globally. This retrospective cohort analysis assessed the pneumonia burden and related healthcare resource utilization and costs in the at-risk (low, medium, and high-risk) adult patients in Dubai...

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Autores principales:	Sara Ahmad Mohammad Al Dallal, Mohamed Farghaly, Ahmed Ghorab, Mostafa Elaassar, Hammam Haridy, Nancy Awad, Badarinath Chickballapur Ramachandrachar, Ashok Natarajan
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/adf3f575d3b9441f9cb45c06c79bb7c3
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spelling	oai:doaj.org-article:adf3f575d3b9441f9cb45c06c79bb7c32021-12-02T20:08:44ZReal-world evaluation of costs of illness for pneumonia in adult patients in Dubai-A claims database study.1932-620310.1371/journal.pone.0256856https://doaj.org/article/adf3f575d3b9441f9cb45c06c79bb7c32021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0256856https://doaj.org/toc/1932-6203<h4>Background</h4>Pneumonia is a significant cause of morbidity and mortality among adults globally. This retrospective cohort analysis assessed the pneumonia burden and related healthcare resource utilization and costs in the at-risk (low, medium, and high-risk) adult patients in Dubai, United Arab Emirates (UAE).<h4>Methods</h4>The claims data from January 1, 2014 to June 30, 2019 were extracted from the Dubai Real-World Claims Database for patients, aged ≥18 year, having at least 1 pneumonia claim. Data for the inpatient, outpatient and emergency visits were assessed for 12-months, before (pre-index) and after (follow-up) a pneumonia episode. Healthcare costs were calculated based on dollar value of 2020.<h4>Results</h4>Total 48,562 records of eligible patients were analyzed (mean age = 39.9 years; low [62.1%], medium [36.2%] and high [1.7%] risk cohorts). Mean all-cause healthcare costs were approximately >45% higher in the follow-up period (1,947 USD/patient) versus pre-index period (1,327 USD/patient). During follow-up period, the mean annual pneumonia incidence rate was 1.3 episodes, with a similar pattern across all cohorts. Overall, mean claims and costs (USD) per patient (all-cause) were highest in the high-risk cohort in the follow-up period (claims: overall, 11.6; high-risk, 22.0; medium-risk, 13.9; low-risk, 9.9; costs: high-risk, 14,184; medium-risk, 2,240; low-risk, 1,388). Similarly, the mean pneumonia-related costs (USD) per patient were highest for the high-risk cohort (overall: 1,305; high-risk, 10,207; medium-risk, 1,283; low-risk, 882), however, the claims were similar across cohorts (claims/patient: overall: 2.0; high-risk, 1.9; medium-risk, 2.2; low-risk, 1.9). Most all-cause and pneumonia-related costs were due to inpatient visits (4,901 and 4,818 USD respectively), while outpatient (1,232 and 166 USD respectively) and emergency visits (347 and 206 USD respectively) contributed significantly lesser.<h4>Conclusions</h4>Pneumonia imposes a significant healthcare burden in the UAE, especially in the high-risk patients with severe comorbidities. These findings would guide clinicians and policy makers to make informed decisions.Sara Ahmad Mohammad Al DallalMohamed FarghalyAhmed GhorabMostafa ElaassarHammam HaridyNancy AwadBadarinath Chickballapur RamachandracharAshok NatarajanPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 9, p e0256856 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Sara Ahmad Mohammad Al Dallal Mohamed Farghaly Ahmed Ghorab Mostafa Elaassar Hammam Haridy Nancy Awad Badarinath Chickballapur Ramachandrachar Ashok Natarajan Real-world evaluation of costs of illness for pneumonia in adult patients in Dubai-A claims database study.
description	<h4>Background</h4>Pneumonia is a significant cause of morbidity and mortality among adults globally. This retrospective cohort analysis assessed the pneumonia burden and related healthcare resource utilization and costs in the at-risk (low, medium, and high-risk) adult patients in Dubai, United Arab Emirates (UAE).<h4>Methods</h4>The claims data from January 1, 2014 to June 30, 2019 were extracted from the Dubai Real-World Claims Database for patients, aged ≥18 year, having at least 1 pneumonia claim. Data for the inpatient, outpatient and emergency visits were assessed for 12-months, before (pre-index) and after (follow-up) a pneumonia episode. Healthcare costs were calculated based on dollar value of 2020.<h4>Results</h4>Total 48,562 records of eligible patients were analyzed (mean age = 39.9 years; low [62.1%], medium [36.2%] and high [1.7%] risk cohorts). Mean all-cause healthcare costs were approximately >45% higher in the follow-up period (1,947 USD/patient) versus pre-index period (1,327 USD/patient). During follow-up period, the mean annual pneumonia incidence rate was 1.3 episodes, with a similar pattern across all cohorts. Overall, mean claims and costs (USD) per patient (all-cause) were highest in the high-risk cohort in the follow-up period (claims: overall, 11.6; high-risk, 22.0; medium-risk, 13.9; low-risk, 9.9; costs: high-risk, 14,184; medium-risk, 2,240; low-risk, 1,388). Similarly, the mean pneumonia-related costs (USD) per patient were highest for the high-risk cohort (overall: 1,305; high-risk, 10,207; medium-risk, 1,283; low-risk, 882), however, the claims were similar across cohorts (claims/patient: overall: 2.0; high-risk, 1.9; medium-risk, 2.2; low-risk, 1.9). Most all-cause and pneumonia-related costs were due to inpatient visits (4,901 and 4,818 USD respectively), while outpatient (1,232 and 166 USD respectively) and emergency visits (347 and 206 USD respectively) contributed significantly lesser.<h4>Conclusions</h4>Pneumonia imposes a significant healthcare burden in the UAE, especially in the high-risk patients with severe comorbidities. These findings would guide clinicians and policy makers to make informed decisions.
format	article
author	Sara Ahmad Mohammad Al Dallal Mohamed Farghaly Ahmed Ghorab Mostafa Elaassar Hammam Haridy Nancy Awad Badarinath Chickballapur Ramachandrachar Ashok Natarajan
author_facet	Sara Ahmad Mohammad Al Dallal Mohamed Farghaly Ahmed Ghorab Mostafa Elaassar Hammam Haridy Nancy Awad Badarinath Chickballapur Ramachandrachar Ashok Natarajan
author_sort	Sara Ahmad Mohammad Al Dallal
title	Real-world evaluation of costs of illness for pneumonia in adult patients in Dubai-A claims database study.
title_short	Real-world evaluation of costs of illness for pneumonia in adult patients in Dubai-A claims database study.
title_full	Real-world evaluation of costs of illness for pneumonia in adult patients in Dubai-A claims database study.
title_fullStr	Real-world evaluation of costs of illness for pneumonia in adult patients in Dubai-A claims database study.
title_full_unstemmed	Real-world evaluation of costs of illness for pneumonia in adult patients in Dubai-A claims database study.
title_sort	real-world evaluation of costs of illness for pneumonia in adult patients in dubai-a claims database study.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/adf3f575d3b9441f9cb45c06c79bb7c3
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Real-world evaluation of costs of illness for pneumonia in adult patients in Dubai-A claims database study.

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