Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

The UK Biobank provides data for three depression-related phenotypes. Here, Howard et al. perform a genome-association study for broad depression, probable major depressive disorder (MDD) and hospital record-coded MDD in up to 322,580 UK Biobank participants which highlights excitatory synaptic path...

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Autores principales:	David M. Howard, Mark J. Adams, Masoud Shirali, Toni-Kim Clarke, Riccardo E. Marioni, Gail Davies, Jonathan R. I. Coleman, Clara Alloza, Xueyi Shen, Miruna C. Barbu, Eleanor M. Wigmore, Jude Gibson, 23andMe Research Team, Saskia P. Hagenaars, Cathryn M. Lewis, Joey Ward, Daniel J. Smith, Patrick F. Sullivan, Chris S. Haley, Gerome Breen, Ian J. Deary, Andrew M. McIntosh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/adf50ca61d2649f090bd2c0b4964ced4
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spelling	oai:doaj.org-article:adf50ca61d2649f090bd2c0b4964ced42021-12-02T16:49:51ZGenome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways10.1038/s41467-018-03819-32041-1723https://doaj.org/article/adf50ca61d2649f090bd2c0b4964ced42018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03819-3https://doaj.org/toc/2041-1723The UK Biobank provides data for three depression-related phenotypes. Here, Howard et al. perform a genome-association study for broad depression, probable major depressive disorder (MDD) and hospital record-coded MDD in up to 322,580 UK Biobank participants which highlights excitatory synaptic pathways.David M. HowardMark J. AdamsMasoud ShiraliToni-Kim ClarkeRiccardo E. MarioniGail DaviesJonathan R. I. ColemanClara AllozaXueyi ShenMiruna C. BarbuEleanor M. WigmoreJude Gibson23andMe Research TeamSaskia P. HagenaarsCathryn M. LewisJoey WardDaniel J. SmithPatrick F. SullivanChris S. HaleyGerome BreenIan J. DearyAndrew M. McIntoshNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q David M. Howard Mark J. Adams Masoud Shirali Toni-Kim Clarke Riccardo E. Marioni Gail Davies Jonathan R. I. Coleman Clara Alloza Xueyi Shen Miruna C. Barbu Eleanor M. Wigmore Jude Gibson 23andMe Research Team Saskia P. Hagenaars Cathryn M. Lewis Joey Ward Daniel J. Smith Patrick F. Sullivan Chris S. Haley Gerome Breen Ian J. Deary Andrew M. McIntosh Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
description	The UK Biobank provides data for three depression-related phenotypes. Here, Howard et al. perform a genome-association study for broad depression, probable major depressive disorder (MDD) and hospital record-coded MDD in up to 322,580 UK Biobank participants which highlights excitatory synaptic pathways.
format	article
author	David M. Howard Mark J. Adams Masoud Shirali Toni-Kim Clarke Riccardo E. Marioni Gail Davies Jonathan R. I. Coleman Clara Alloza Xueyi Shen Miruna C. Barbu Eleanor M. Wigmore Jude Gibson 23andMe Research Team Saskia P. Hagenaars Cathryn M. Lewis Joey Ward Daniel J. Smith Patrick F. Sullivan Chris S. Haley Gerome Breen Ian J. Deary Andrew M. McIntosh
author_facet	David M. Howard Mark J. Adams Masoud Shirali Toni-Kim Clarke Riccardo E. Marioni Gail Davies Jonathan R. I. Coleman Clara Alloza Xueyi Shen Miruna C. Barbu Eleanor M. Wigmore Jude Gibson 23andMe Research Team Saskia P. Hagenaars Cathryn M. Lewis Joey Ward Daniel J. Smith Patrick F. Sullivan Chris S. Haley Gerome Breen Ian J. Deary Andrew M. McIntosh
author_sort	David M. Howard
title	Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
title_short	Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
title_full	Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
title_fullStr	Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
title_full_unstemmed	Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
title_sort	genome-wide association study of depression phenotypes in uk biobank identifies variants in excitatory synaptic pathways
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/adf50ca61d2649f090bd2c0b4964ced4
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Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

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