Predictive design of sigma factor-specific promoters
Automated design tools and tailored subunits are beneficial in fine-tuning all components of a complex genetic circuit. Here the authors create E. coli and B. subtilis promoter libraries using FACS and HTS, from which an online promoter design tool has been developed using CNN.
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Main Authors: | Maarten Van Brempt, Jim Clauwaert, Friederike Mey, Michiel Stock, Jo Maertens, Willem Waegeman, Marjan De Mey |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Online Access: | https://doaj.org/article/ae04ea037b8d404a8d08ac51c6a9e3ae |
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