The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

Infants born to obese mothers have altered microbiome and increased risk of obesity and NAFLD. Here the authors establish causality by showing that maternal obesity-shaped infant gut microbiome induces macrophage dysfunction, inflammation, and diet-induced metabolic disease in germ-free mice.

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Auteurs principaux: Taylor K. Soderborg, Sarah E. Clark, Christopher E. Mulligan, Rachel C. Janssen, Lyndsey Babcock, Diana Ir, Bridget Young, Nancy Krebs, Dominick J. Lemas, Linda K. Johnson, Tiffany Weir, Laurel L. Lenz, Daniel N. Frank, Teri L. Hernandez, Kristine A. Kuhn, Angelo D’Alessandro, Linda A. Barbour, Karim C. El Kasmi, Jacob E. Friedman
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/ae080f0844c14d709b3a8306cb9877f4
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