Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry

IMPORTANCE:. Even with its proclivity for older age, coronavirus disease 2019 has been shown to affect all age groups. However, there remains a lack of research focused primarily on the young adult population. OBJECTIVES:. To describe the epidemiology and outcomes of coronavirus disease 2019 and ide...

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Autores principales:	Sandeep Tripathi, MD, MS, Imran A. Sayed, MD, Heda Dapul, MD, Jeremy S. McGarvey, MS, Jennifer A. Bandy, RN, Karen Boman, BS, Vishakha K. Kumar, MD, MBA, Vikas Bansal, MBBS, MPH, Lynn Retford, CAE, Sreekanth Cheruku, MD, MPH, Margit Kaufman, MD, FASA, Smith F. Heavner, MS, RN, Valerie C. Danesh, PhD, RN, Catherine A. St. Hill, DVM, PhD, Ashish K. Khanna, MD, Utpal Bhalala, MD, Rahul Kashyap, MBBS, MBA, Ognjen Gajic, MD, MS, Allan J. Walkey, MD, MS, Katja M. Gist, DO, MSc, for The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group, Jean-Baptiste Mesland, Pierre Henin, Hélène Petre, Isabelle Buelens, Anne-Catherine Gerard, Philippe Clevenbergh, Rolando Claure-Del Granado, Jose A. Mercado, Esdenka Vega-Terrazas, Maria F. Iturricha-Caceres, Ruben Garza, Eric Chu, Victoria Chan, Oscar Y Gavidia, Felipe Pachon, Yeimy A Sanchez, Mohamed El Kassas, Mohamed Badr, Ahmed Tawheed, Hend Yahia, Sierra-Hoffman, Fernando Valerio, Oscar Diaz, Jose Luis Ramos Coello, Guillermo Perez, Ana Karen Vallecillo Lizardo, Gabina María Reyes Guillen, Helin Archaga Soto, Mradul Kumar Daga, Munisha Agarwal, Ishan Rohtagi, Anusha Cherian, Sreejith Parameswaran, Magesh Parthiban, Menu Priya A., Girish Vadgaonkar, Rekha Ediga, Shilpa Basety, Shwetha Dammareddy, Phani Sreeharsha Kasumalla, Sridhar Papani, Mahesh Kamuram, Smitha S. Segu, Tuhin Chakraborty, Epcebha Joyce, Umamaheswara Raju, Janaki Manduva, Naresh Kolakani, Shreeja Sripathi, Sheetal Chaitanya, Surapaneni Krishna Mohan, Ekambaram Jyothisree, Kamlesh Kumar Agrawal, Vijendra Baghel, Kirti Kumar Patel, Nooshin Dalili, Mohsen Nafa, Sandeep Tripathi, Yuki Itagaki, Akira Kodate, Reina Suzuki, Yuki Takahashi, Koyo Moriki, Michihito Kyo, Masamitsu Sanui, Sho Horikita, Wataru Matsuda, Shu Tahara, Mineji Hayakawa, Kunihiko Maekawa, Takuya Shiga, Yudai Iwasaki, Abdulrahman AlFares, Rene Rodriguez-Gutierrez, Jose Gerardo Gonzalez-Gonzalez, Alejandro Salcido-Montenegro, Adrian Camacho-Ortiz, Fatimah Hassan-Hanga, Hadiza Galadanci, Abubakar Shehu Gezawa, Halima M. S. Kabara, Taiwo Gboluwaga Amole, Halima Kabir, Dalha Gwarzo, Haliru, Abdullahi S Ibrahim, Muhammad Sohaib Asghar, Mashaal Syed, Syed Anosh Ali Naqvi, Igor Borisovich Zabolotskikh, Konstantin Dmitrievich Zybin, Sergey Vasilevich Sinkov, Tatiana Sergeevna Musaeva, Marwa Ridha Amer, Mohammed Abdullah Bawazeer, Talal I. Dahhan, Eiad Kseibi, Abid Shahzad Butt, Syed Moazzum Khurshid, Muath Rabee, Mohammed Abujazar, Razan Alghunaim, Maal Abualkhair, Abeer Turki AlFirm, Razan K Alamoudi, Hassan M. AlSharif, Sarah A. Almazwaghi, Mohammed S Elsakran, Mohamed A Aid, Mouaz A Darwich, Omnia M Hagag, Salah A Ali, Alona rocacorba, Kathrine Supeña, Efren Ray Juane, Jenalyn Medina, Jowany Baduria, Mohammed A Almazyad, Mohammed I Alarifi, Jara M Macarambon, Ahmad Abdullah Bukhari, Hussain A. 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Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer 2021
Materias:	Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Acceso en línea:	https://doaj.org/article/ae0fb2090d944883bab4c102a169e8a4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ae0fb2090d944883bab4c102a169e8a4
record_format	dspace
institution	DOAJ
collection	DOAJ
language	EN
topic	Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
spellingShingle	Medical emergencies. Critical care. Intensive care. First aid RC86-88.9 Sandeep Tripathi, MD, MS Imran A. Sayed, MD Heda Dapul, MD Jeremy S. McGarvey, MS Jennifer A. Bandy, RN Karen Boman, BS Vishakha K. Kumar, MD, MBA Vikas Bansal, MBBS, MPH Lynn Retford, CAE Sreekanth Cheruku, MD, MPH Margit Kaufman, MD, FASA Smith F. Heavner, MS, RN Valerie C. Danesh, PhD, RN Catherine A. St. Hill, DVM, PhD Ashish K. Khanna, MD Utpal Bhalala, MD Rahul Kashyap, MBBS, MBA Ognjen Gajic, MD, MS Allan J. Walkey, MD, MS Katja M. Gist, DO, MSc for The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group Jean-Baptiste Mesland Pierre Henin Hélène Petre Isabelle Buelens Anne-Catherine Gerard Philippe Clevenbergh Rolando Claure-Del Granado Jose A. Mercado Esdenka Vega-Terrazas Maria F. Iturricha-Caceres Ruben Garza Eric Chu Victoria Chan Oscar Y Gavidia Felipe Pachon Yeimy A Sanchez Mohamed El Kassas Mohamed Badr Ahmed Tawheed Ahmed Tawheed Hend Yahia Sierra-Hoffman Fernando Valerio Oscar Diaz Jose Luis Ramos Coello Guillermo Perez Ana Karen Vallecillo Lizardo Gabina María Reyes Guillen Helin Archaga Soto Mradul Kumar Daga Munisha Agarwal Ishan Rohtagi Anusha Cherian Sreejith Parameswaran Magesh Parthiban Menu Priya A. Girish Vadgaonkar Rekha Ediga Shilpa Basety Shwetha Dammareddy Phani Sreeharsha Kasumalla Sridhar Papani Mahesh Kamuram Smitha S. Segu Tuhin Chakraborty Epcebha Joyce Umamaheswara Raju Janaki Manduva Naresh Kolakani Shreeja Sripathi Sheetal Chaitanya Surapaneni Krishna Mohan Ekambaram Jyothisree Kamlesh Kumar Agrawal Vijendra Baghel Kirti Kumar Patel Nooshin Dalili Mohsen Nafa Sandeep Tripathi Yuki Itagaki Akira Kodate Reina Suzuki Akira Kodate Yuki Takahashi Koyo Moriki Michihito Kyo Reina Suzuki Masamitsu Sanui Sho Horikita Wataru Matsuda Reina Suzuki Shu Tahara Mineji Hayakawa Kunihiko Maekawa Takuya Shiga Yudai Iwasaki Abdulrahman AlFares Rene Rodriguez-Gutierrez Jose Gerardo Gonzalez-Gonzalez Alejandro Salcido-Montenegro Adrian Camacho-Ortiz Fatimah Hassan-Hanga Hadiza Galadanci Abubakar Shehu Gezawa Halima M. S. Kabara Taiwo Gboluwaga Amole Halima Kabir Dalha Gwarzo Haliru, Abdullahi S Ibrahim Muhammad Sohaib Asghar Mashaal Syed Syed Anosh Ali Naqvi Igor Borisovich Zabolotskikh Konstantin Dmitrievich Zybin Sergey Vasilevich Sinkov Tatiana Sergeevna Musaeva Marwa Ridha Amer Mohammed Abdullah Bawazeer Talal I. Dahhan Eiad Kseibi Abid Shahzad Butt Syed Moazzum Khurshid Muath Rabee Mohammed Abujazar Razan Alghunaim Maal Abualkhair Abeer Turki AlFirm Eiad Kseibi Syed Moazzum Khurshid Muath Rabee Mohammed Abujazar Razan Alghunaim Razan K Alamoudi Hassan M. AlSharif Sarah A. Almazwaghi Mohammed S Elsakran Mohamed A Aid Mouaz A Darwich Omnia M Hagag Salah A Ali Alona rocacorba Kathrine Supeña Efren Ray Juane Jenalyn Medina Jowany Baduria Mohammed A Almazyad Mohammed I Alarifi Jara M Macarambon Ahmad Abdullah Bukhari Hussain A. Albahrani Kazi N Asfina Kaltham M Aldossary Predrag D Stevanovic Dejan S Stojakov Duska K Ignjatovic Suzana C Bojic Marina M Bobos Irina B Nenadic Milica S Zaric Marko D Djuric Vladimir R Djukic Bojan Kovacevic Jovana Bojicic Marija Zdravkovic Zoran Todorovic Viseslav Popadic Slobodan Klasnja Santiago Y. Teruel Belen C. Martin Santiago Y. Teruel Himat Sulaimonov Firuza Khudonazarova Nabi Bakhtibekov Nekruz Jamshedov Uluhan Sili Huseyin Bilgin Pinar Ay Varsha P Gharpure Usman Raheemi Kenneth W. Dodd Nicholas Goodmanson Kathleen Hesse Paige Bird Chauncey Weinert Nathan Schoenrade Abdulrahman Altaher Esmael Mayar Matthew Aronson Tyler Cooper Monica Logan Brianna Miner Gisele Papo Eric M. Siegal Phyllis Runningen Catherine A. St. Hill Roman R. Melamed David M. Tierney Love A. Patel Vino S. Raj Barite U. Dawud Narayana Mazumder Abbey Sidebottom Alena M. Guenther Benjamin D. Krehbiel Nova J. Schmitz Stacy L. Jepsen Abhijit A Raval Andrea Franks Katherine Irby Ronald C. Sanders, Jr. Glenda Hefley Anmol Kharbanda Sunil Jhajhria Zachary Fyffe Stephen Capizzi Bethany Alicie Martha Green Lori Crockarell Amelia Drennan Kathleen Dubuque Tonya Fambrough Nikole Gasaway Briana Krantz Peiman Nebi Jan Orga Margaret Serfass Alina Simion Kimberly Warren Cassie Wheeler CJ Woolman Andrew S. Moyer George M. Verghese Andrea Sikora Newsome Christy C. Forehand Rebecca Bruning Timothy W. Jones Moldovan Sabov Fatema Zaidi Fiona Tissavirasingham Dhatri Malipeddi Jarrod M Mosier Karen Lutrick Beth Salvagio Campbell Cathleen Wilson Patrick Rivers Jonathan Brinks Mokenge Ndiva Mongoh Boris Gilson Donna Lee Armaignac Don Parris Maria Pilar Zuniga Ilea Vargas Viviana Boronat Anneka Hutton Navneet Kaur Prashank Neupane Nohemi Sadule-Rios Lourdes M. Rojas Aashish Neupane Priscilla Rivera Carlos Valle Carlos Gregory Vincent Mahesh Amin Mary E Schelle Amanda Steadham Christopher M Howard Cameron McBride Jocelyn Abraham Orlando Garner Katherine Richards Keegan Collins Preethi Antony Sindhu Mathew Valerie C. Danesh Gueorgui Dubrocq Amber L. Davis Marissa J Hammers ill M. McGahey Amanda C. Farris Elisa Priest Robyn Korsmo Lorie Fares Kathy Skiles Susan M. Shor Kenya Burns Corrie A Dowell Melody Flores Lindsay Newman Debora A Wilk Jason Ettlinger Jaccallene Bomar Himani Darji Alejandro Arroliga Alejandro C Arroliga Corrie A. Dowell Gabriela Hope Conzales Melody Flores Lindsay Newman Debora A. Wilk Jason Ettlinger Himani Darji Jaccallene Bomar Paras B. Khandhar Elizabeth Kring Valerie M. Banner-Goodspeed Somnath Bose Lauren E. Kelly Melisa Joseph Marie McGourty Krystal Capers Benjamin Hoenig Maria C. Karamourtopoulos Anica C. Law Elias N. Baedorf Kassis Allan J. Walkey Sushrut S. Waikar Michael A. Garcia Mia Colona Zoe Kibbelaar Michael Leong Daniel Wallman Kanupriya Soni Jennifer Maccarone Joshua Gilman Ycar Devis Joseph Chung Munizay Paracha David N. Lumelsky Madeline DiLorenzo Najla Abdurrahman Shelsey Johnson Andrew M. Hersh Stephanie L Wachs Brittany S. Swigger Stephanie L Wachs Lauren A. Sattler Michael N. Moulton Kimberly Zammit J Patrick William McGrath Maya Loeffler R Chilbert Aaron S. Miller Edwin L. Anderson Rosemary Nagy Ravali R. Inja Raghavendra Tirupathi Alymer Tang Arshad Safi Cindy Green Jackie Newell Rayan E. Ihle Shelda A. Martin Elaine A. Davis Katja M. Gist Imran A Sayed John Brinton Larisa Strom Kathleen Chiotos Allison M. Blatz Giyoung Lee Ryan H. Burnett Guy I. Sydney Danielle M. Traynor Karissa Nauert Annika Gonzalez Mariel Bagley Anita Santpurkar Salim Surani Joshua White Aftab Khan Rahul Dhahwal Sreekanth Cheruku Farzin Ahmed Christopher Deonarine Ashley Jones Mohammad-Ali Shaikh David Preston Jeanette Chin Vidula Vachharajani Abhijit Duggal Prabalini Rajendram Omar Mehkri Siddharth Dugar Michelle Biehl Gretchen Sacha Stuart Houltham Alexander King Kiran Ashok Bryan Poynter Mary Beukemann Richard Rice Susan Gole Valerie Shaner Adarsh Conjeevaram Michelle Ferrari Narendrakumar Alappan Steven Minear Jaime Hernandez-Montfort Syed Sohaib Nasim Ravi Sunderkrishnan Debasis Sahoo Patrick S. Milligan Sandeep K. Gupta Joy M. Koglin Regina Gibson Lana Johnson Felicia Preston Crimson Scott Bethany Nungester Steven K. Daugherty Sam Atkinson Kelly Shrimpton Sidney Ontai Brian Contreras Uzoma Obinwanko Nneka Amamasi Amir Sharafi Sarah Lee Zahia Esber Chetna Jinjvadia Kimberly Welker Francis M. Maguire Jessica Timmer Raquel R Bartz Vijay Krishnamoorthy Bryan Kraft Aaron Pulsipher Eugene Friedman Sachin Mehta Margit Kaufman Gregg Lobel Nisha Gandhi Amr Abdelaty Elizabeth Shaji Kiana Lim Juan Marte Dani Ashley Sosa David P. Yamane Ivy Benjenk Nivedita Prasanna Smith F. Heavner-Sullivan Prera J. Roth Banu Sivaraj Haley Fulton Madison G Herin Marissa Crum Morgan E. Fretwell Emily-Rose Zhou Christine Waller Kara Kallies Christine Waller Jonean Thorsen Alec Fitzsimmons Haley Olsen Heda R. Dapul Sourabh Verma Alan Salas Ariel Daube Michelle Korn Michelle Ramirez Logi Rajagopalan Laura Santos Orma Smalls Atul Malhotra Abdurrahman Husain Qais Zawaydeh J.H. Steuernagle Steven Q. Davis Valentina Jovic Valentina Jovic Max Masuda Amanda Hayes Katharine Nault Michael Smith William Snow Riley Liptak Hannah Durant Valerie Pendleton Alay Nanavati Risa Mrozowsk LiManoj K Gupta Franscene E. Oulds Akshay Nandavar Yuk Ming Liu Sarah Zavala Sarah Zavala Esther Shim Ronald A. Reilkoff Julia A. Heneghan Sarah Eichen Lexie Goertzen Scott Rajala Ghislaine Feussom Ben Tang Christine C. Junia Robert Lichtenberg Hasrat Sidhu Diana Espinoza Shelden Rodrigues Maria Jose Zabala Daniela Goyes Ammu Susheela Buddhi Hatharaliyadda Naveen Rameshkumar Amulya Kasireddy Genessis Maldonado Lisseth Beltran Akshata Chaugule Hassan Khan Namrata Patil Ruhi Patil Rodrigo Cartin-Ceba Ayan Sen Amanda Palacios Giyth M. Mahdi Rahul Kashyap Ognjen Gajic Vikas Bansal Aysun Tekin Amos Lal John C. O’Horo Neha N. Deo Mayank Sharma Shahraz Qamar Cory J. Kudrna Juan Pablo Domecq Garces Abigail T. La Nou Marija Bogojevic Devang Sanghavi Pramod Guru Karthik Gnanapandithan Hollie Saunders Zachary Fleissner Juan Garcia Alejandra Yu Lee Mateus Siva Naga Yarrarapu Syed Anjum Khan Juan Pablo Domecq Nitesh Kumar Jain Thoyaja Koritala Alexander Bastidas Gabriela Orellana Adriana Briceno Bierwirth Eliana Milazzo Juan Guillermo Sierra Thao Dang Amy B. Christie Dennis W. Ashley Rajani Adiga Rahul S Nanchal Paul A Bergl Jennifer L Peterson Travis Yamanaka Nicholas A. Barreras Michael Markos Anita Fareeduddin Rohan Mehta Chakradhar Venkata Miriam Engemann Annamarie Mantese Yasir Tarabichi Adam Perzynski Christine Wang Dhatri Kotekal Adriana C Briceno Bierwirth Gabriela M Orellana Gerardo Catalasan Shohana Ahmed Carlos F Matute Ahmad Hamdan Ivania Salinas Genesis Del Nogal Angel Tejada Anna Eschler Mary Hejna Emily Lewandowski Kristen Kusmierski Clare Martin Jen-Ting Chen Aluko Hope Zoe Tsagaris Elise Ruen Aram Hambardzumyan Prithvi Sendi Meghana Nadiger Balagangadhar Totapally Bhagat S. Aulakh Sandeep Tripathi Jennifer A. Bandy Lisa M. Kreps Dawn R. Bollinger Jennifer A. Bandy Roger Scott Stienecker Andre G. Melendez Tressa A. Brunner Sue M Budzon Jessica L. Heffernan Janelle M. Souder Tracy L. Miller Andrea G. Maisonneuve Roberta E. Redfern Jessica Shoemaker Jennifer Micham Lynn Kenney Gabriel Naimy Sara Utley Holly Balcer Kerry P. J. Pulver Jennifer Yehle Alicia Weeks Terra Inman Brian L. Delmonaco Anthony Franklin Mitchell Heath Antonia L. Vilella Sara B. Kutner Kacie Clark Danielle Moore Shina Menon John K McGuire Deana Rich Harry L. Anderson, III Dixy Rajkumar Ali Abunayla Jerrilyn Heiter Howard A. Zaren Stephanie J. Smith Grant C. Lewis Lauren Seames Cheryl Farlow Judy Miller Gloria Broadstreet John Lin Cindy Terrill Brock Montgomery Sydney Reyes Summer Reyes Alex Plattner Anthony Martinez Micheal Allison Aniket Mittal Rafael Ruiz Aleta Skaanland Robert Ross Umang Patel Jordesha Hodge KrunalKumar Patel Shivani Dalal Himanshu Kavani Sam Joseph Michael A. Bernstein Ian K. Goff Matthew Naftilan Amal Mathew Deborah Williams Sue Murdock Maryanne Ducey Kerianne Nelson Paul K Mohabir Connor G O’Brien Komal Dasani William Marx Ioana Amzuta Asad J. Choudhry Mohammad T. Azam Kristina L Carter Michael A Olmos Brittany M Parker Julio Quintanilla Tara A Craig Brendon J Clough Jeffrey T Jameson Neha Gupta Tracy L Jones Shonda C Ayers Amy B Harrell Dr.Brent R Brown Utpal S. Bhalala Joshua Kuehne Melinda Garcia Morgan Beebe Heather Herrera Chris Fiack Stephanie Guo May Vawer Beth Blackburn Megan Edwards Caleb Darby Kristy Page Amanda Brown Jessie McAbee Katherine A. Belden Michael Baram Devin M. Weber Rosalie DePaola Yuwei Xia Hudson Carter Aaron Tolley Mark Steele Laurie Kemble Joshua L. Denson A. Scott Gillet Margo Brown Rachael Stevens Andrew Wetherbie Kevin Tea Mathew Moore Abdurrahman Husain Atul Malhotra Qais Zawaydeh Benjamin J Sines Thomas J Bice Emily A. Vail Susannah Nicholson Rachelle B. Jonas AnnaRose E. Dement William Tang Mark DeRosa Robert E. Villarreal Rajany V. Dy Alfredo Iardino Jill Sharma Richard Czieki Julia Christopher Ryan Lacey Marwan Mashina Kushal Patel Erica C. Bjornstad Nancy M. Tofil Scott House Isabella Aldana Nikhil K. Meena Jose D. Caceres Nikhil K Meena Sarenthia M. Epps Harmeen Goraya Kelsey R. Besett Ryan James Lana Y. Abusalem Akash K. Patel Lana S Hasan Dina Gomaa Michael Goodman Devin Wakefield Anthony Spuzzillo John O. Shinn, II Azra Bihorac Tezcan Ozrazgat Baslanti George Omalay Haleh Hashemighouchani Julie S. Cupka Matthew M Ruppert Patrick W. McGonagill Colette Galet Janice Hubbard David Wang Lauren Allan Aditya Badheka Madhuradhar Chegondi Usman Nazir Garrett Rampon Jake Riggle Nathan Dismang Vicki Montgomery Janice Sullivan Sarah Morris Jennifer Nason Roger A. Alvarez Amarilys Alarcon-Calderon Marie Anne Sosa Sunita K. Mahabir Mausam J. Patel Pauline Park Andrew Admon Sinan Hanna Rishi Chanderraj Maria Pliakas Ann Wolski Jennifer Cirino Dima Dandachi Hariharan Regunath Maraya N. Camazine Grant. E. Geiger Abdoulie O. Njai Baraa M. Saad Faraaz Ali Shah Byron Chuan Sagar L. Rawal Manal Piracha Joseph E. Tonna Nicholas M. Levin Kayte Suslavich Rachel Tsolinas Zachary T. Fica Chloe R. Skidmore Renee D. Stapleton Anne E. Dixon Olivia Johnson Sara S. Ardren Stephanie Burns Anna Raymond Erika Gonyaw Kevin Hodgdon Chloe Housenger Benjamin Lin Karen McQuesten Heidi Pecott-Grimm Julie Sweet Sebastian Ventrone Nita Khandelwal T. Eoin West Ellen S. Caldwell Lara Lovelace-Macon Navya Garimella Denisse B. Dow Murtaza Akhter Rania Abdul Rahman Mary Mulrow Erin M. Wilfong Kelsi Vela Ashish K. Khanna Lynne Harris Bruce Cusson Jacob Fowler David Vaneenenaam Glen McKinney Imoh Udoh Kathleen Johnson Patrick G. Lyons Andrew P Michelson Sara S. Haluf Lauren M. Lynch Nguyet M. Nguyen Aaron Steinberg Nicholas Braus Vishwanath Pattan Jessica Papke Ismail Jimada Nida Mhid Samuel Chakola Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry
description	IMPORTANCE:. Even with its proclivity for older age, coronavirus disease 2019 has been shown to affect all age groups. However, there remains a lack of research focused primarily on the young adult population. OBJECTIVES:. To describe the epidemiology and outcomes of coronavirus disease 2019 and identify the risk factors associated with critical illness and mortality in hospitalized young adults. DESIGN, SETTINGS, AND PARTICIPANTS:. A retrospective cohort study of the Society of Critical Care Medicine’s Viral Infection and Respiratory Illness Universal Study registry. Patients 18–40 years old, hospitalized from coronavirus disease 2019 from March 2020 to April 2021, were included in the analysis. MAIN OUTCOMES AND MEASURES:. Critical illness was defined as a composite of mortality and 21 predefined interventions and complications. Multivariable logistic regression was used to assess associations with critical illness and mortality. RESULTS:. Data from 4,005 patients (152 centers, 19 countries, 18.6% non-U.S. patients) were analyzed. The median age was 32 years (interquartile range, 27–37 yr); 51% were female, 29.4% Hispanic, and 42.9% had obesity. Most patients (63.2%) had comorbidities, the most common being hypertension (14.5%) and diabetes (13.7%). Hospital and ICU mortality were 3.2% (129/4,005) and 8.3% (109/1,313), respectively. Critical illness occurred in 25% (n = 996), and 34.3% (n = 1,376) were admitted to the ICU. Older age (p = 0.03), male sex (adjusted odds ratio, 1.83 [95% CI, 1.2–2.6]), and obesity (adjusted odds ratio, 1.6 [95% CI, 1.1–2.4]) were associated with hospital mortality. In addition to the above factors, the presence of any comorbidity was associated with critical illness from coronavirus disease 2019. Multiple sensitivity analyses, including analysis with U.S. patients only and patients admitted to high-volume sites, showed similar risk factors. CONCLUSIONS:. Among hospitalized young adults, obese males with comorbidities are at higher risk of developing critical illness or dying from coronavirus disease 2019.
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author	Sandeep Tripathi, MD, MS Imran A. Sayed, MD Heda Dapul, MD Jeremy S. McGarvey, MS Jennifer A. Bandy, RN Karen Boman, BS Vishakha K. Kumar, MD, MBA Vikas Bansal, MBBS, MPH Lynn Retford, CAE Sreekanth Cheruku, MD, MPH Margit Kaufman, MD, FASA Smith F. Heavner, MS, RN Valerie C. Danesh, PhD, RN Catherine A. St. Hill, DVM, PhD Ashish K. Khanna, MD Utpal Bhalala, MD Rahul Kashyap, MBBS, MBA Ognjen Gajic, MD, MS Allan J. Walkey, MD, MS Katja M. Gist, DO, MSc for The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group Jean-Baptiste Mesland Pierre Henin Hélène Petre Isabelle Buelens Anne-Catherine Gerard Philippe Clevenbergh Rolando Claure-Del Granado Jose A. Mercado Esdenka Vega-Terrazas Maria F. Iturricha-Caceres Ruben Garza Eric Chu Victoria Chan Oscar Y Gavidia Felipe Pachon Yeimy A Sanchez Mohamed El Kassas Mohamed Badr Ahmed Tawheed Ahmed Tawheed Hend Yahia Sierra-Hoffman Fernando Valerio Oscar Diaz Jose Luis Ramos Coello Guillermo Perez Ana Karen Vallecillo Lizardo Gabina María Reyes Guillen Helin Archaga Soto Mradul Kumar Daga Munisha Agarwal Ishan Rohtagi Anusha Cherian Sreejith Parameswaran Magesh Parthiban Menu Priya A. Girish Vadgaonkar Rekha Ediga Shilpa Basety Shwetha Dammareddy Phani Sreeharsha Kasumalla Sridhar Papani Mahesh Kamuram Smitha S. Segu Tuhin Chakraborty Epcebha Joyce Umamaheswara Raju Janaki Manduva Naresh Kolakani Shreeja Sripathi Sheetal Chaitanya Surapaneni Krishna Mohan Ekambaram Jyothisree Kamlesh Kumar Agrawal Vijendra Baghel Kirti Kumar Patel Nooshin Dalili Mohsen Nafa Sandeep Tripathi Yuki Itagaki Akira Kodate Reina Suzuki Akira Kodate Yuki Takahashi Koyo Moriki Michihito Kyo Reina Suzuki Masamitsu Sanui Sho Horikita Wataru Matsuda Reina Suzuki Shu Tahara Mineji Hayakawa Kunihiko Maekawa Takuya Shiga Yudai Iwasaki Abdulrahman AlFares Rene Rodriguez-Gutierrez Jose Gerardo Gonzalez-Gonzalez Alejandro Salcido-Montenegro Adrian Camacho-Ortiz Fatimah Hassan-Hanga Hadiza Galadanci Abubakar Shehu Gezawa Halima M. S. Kabara Taiwo Gboluwaga Amole Halima Kabir Dalha Gwarzo Haliru, Abdullahi S Ibrahim Muhammad Sohaib Asghar Mashaal Syed Syed Anosh Ali Naqvi Igor Borisovich Zabolotskikh Konstantin Dmitrievich Zybin Sergey Vasilevich Sinkov Tatiana Sergeevna Musaeva Marwa Ridha Amer Mohammed Abdullah Bawazeer Talal I. Dahhan Eiad Kseibi Abid Shahzad Butt Syed Moazzum Khurshid Muath Rabee Mohammed Abujazar Razan Alghunaim Maal Abualkhair Abeer Turki AlFirm Eiad Kseibi Syed Moazzum Khurshid Muath Rabee Mohammed Abujazar Razan Alghunaim Razan K Alamoudi Hassan M. AlSharif Sarah A. Almazwaghi Mohammed S Elsakran Mohamed A Aid Mouaz A Darwich Omnia M Hagag Salah A Ali Alona rocacorba Kathrine Supeña Efren Ray Juane Jenalyn Medina Jowany Baduria Mohammed A Almazyad Mohammed I Alarifi Jara M Macarambon Ahmad Abdullah Bukhari Hussain A. Albahrani Kazi N Asfina Kaltham M Aldossary Predrag D Stevanovic Dejan S Stojakov Duska K Ignjatovic Suzana C Bojic Marina M Bobos Irina B Nenadic Milica S Zaric Marko D Djuric Vladimir R Djukic Bojan Kovacevic Jovana Bojicic Marija Zdravkovic Zoran Todorovic Viseslav Popadic Slobodan Klasnja Santiago Y. Teruel Belen C. Martin Santiago Y. Teruel Himat Sulaimonov Firuza Khudonazarova Nabi Bakhtibekov Nekruz Jamshedov Uluhan Sili Huseyin Bilgin Pinar Ay Varsha P Gharpure Usman Raheemi Kenneth W. Dodd Nicholas Goodmanson Kathleen Hesse Paige Bird Chauncey Weinert Nathan Schoenrade Abdulrahman Altaher Esmael Mayar Matthew Aronson Tyler Cooper Monica Logan Brianna Miner Gisele Papo Eric M. Siegal Phyllis Runningen Catherine A. St. Hill Roman R. Melamed David M. Tierney Love A. Patel Vino S. Raj Barite U. Dawud Narayana Mazumder Abbey Sidebottom Alena M. Guenther Benjamin D. Krehbiel Nova J. Schmitz Stacy L. Jepsen Abhijit A Raval Andrea Franks Katherine Irby Ronald C. Sanders, Jr. Glenda Hefley Anmol Kharbanda Sunil Jhajhria Zachary Fyffe Stephen Capizzi Bethany Alicie Martha Green Lori Crockarell Amelia Drennan Kathleen Dubuque Tonya Fambrough Nikole Gasaway Briana Krantz Peiman Nebi Jan Orga Margaret Serfass Alina Simion Kimberly Warren Cassie Wheeler CJ Woolman Andrew S. Moyer George M. Verghese Andrea Sikora Newsome Christy C. Forehand Rebecca Bruning Timothy W. Jones Moldovan Sabov Fatema Zaidi Fiona Tissavirasingham Dhatri Malipeddi Jarrod M Mosier Karen Lutrick Beth Salvagio Campbell Cathleen Wilson Patrick Rivers Jonathan Brinks Mokenge Ndiva Mongoh Boris Gilson Donna Lee Armaignac Don Parris Maria Pilar Zuniga Ilea Vargas Viviana Boronat Anneka Hutton Navneet Kaur Prashank Neupane Nohemi Sadule-Rios Lourdes M. Rojas Aashish Neupane Priscilla Rivera Carlos Valle Carlos Gregory Vincent Mahesh Amin Mary E Schelle Amanda Steadham Christopher M Howard Cameron McBride Jocelyn Abraham Orlando Garner Katherine Richards Keegan Collins Preethi Antony Sindhu Mathew Valerie C. Danesh Gueorgui Dubrocq Amber L. Davis Marissa J Hammers ill M. McGahey Amanda C. Farris Elisa Priest Robyn Korsmo Lorie Fares Kathy Skiles Susan M. Shor Kenya Burns Corrie A Dowell Melody Flores Lindsay Newman Debora A Wilk Jason Ettlinger Jaccallene Bomar Himani Darji Alejandro Arroliga Alejandro C Arroliga Corrie A. Dowell Gabriela Hope Conzales Melody Flores Lindsay Newman Debora A. Wilk Jason Ettlinger Himani Darji Jaccallene Bomar Paras B. Khandhar Elizabeth Kring Valerie M. Banner-Goodspeed Somnath Bose Lauren E. Kelly Melisa Joseph Marie McGourty Krystal Capers Benjamin Hoenig Maria C. Karamourtopoulos Anica C. Law Elias N. Baedorf Kassis Allan J. Walkey Sushrut S. Waikar Michael A. Garcia Mia Colona Zoe Kibbelaar Michael Leong Daniel Wallman Kanupriya Soni Jennifer Maccarone Joshua Gilman Ycar Devis Joseph Chung Munizay Paracha David N. Lumelsky Madeline DiLorenzo Najla Abdurrahman Shelsey Johnson Andrew M. Hersh Stephanie L Wachs Brittany S. Swigger Stephanie L Wachs Lauren A. Sattler Michael N. Moulton Kimberly Zammit J Patrick William McGrath Maya Loeffler R Chilbert Aaron S. Miller Edwin L. Anderson Rosemary Nagy Ravali R. Inja Raghavendra Tirupathi Alymer Tang Arshad Safi Cindy Green Jackie Newell Rayan E. Ihle Shelda A. Martin Elaine A. Davis Katja M. Gist Imran A Sayed John Brinton Larisa Strom Kathleen Chiotos Allison M. Blatz Giyoung Lee Ryan H. Burnett Guy I. Sydney Danielle M. Traynor Karissa Nauert Annika Gonzalez Mariel Bagley Anita Santpurkar Salim Surani Joshua White Aftab Khan Rahul Dhahwal Sreekanth Cheruku Farzin Ahmed Christopher Deonarine Ashley Jones Mohammad-Ali Shaikh David Preston Jeanette Chin Vidula Vachharajani Abhijit Duggal Prabalini Rajendram Omar Mehkri Siddharth Dugar Michelle Biehl Gretchen Sacha Stuart Houltham Alexander King Kiran Ashok Bryan Poynter Mary Beukemann Richard Rice Susan Gole Valerie Shaner Adarsh Conjeevaram Michelle Ferrari Narendrakumar Alappan Steven Minear Jaime Hernandez-Montfort Syed Sohaib Nasim Ravi Sunderkrishnan Debasis Sahoo Patrick S. Milligan Sandeep K. Gupta Joy M. Koglin Regina Gibson Lana Johnson Felicia Preston Crimson Scott Bethany Nungester Steven K. Daugherty Sam Atkinson Kelly Shrimpton Sidney Ontai Brian Contreras Uzoma Obinwanko Nneka Amamasi Amir Sharafi Sarah Lee Zahia Esber Chetna Jinjvadia Kimberly Welker Francis M. Maguire Jessica Timmer Raquel R Bartz Vijay Krishnamoorthy Bryan Kraft Aaron Pulsipher Eugene Friedman Sachin Mehta Margit Kaufman Gregg Lobel Nisha Gandhi Amr Abdelaty Elizabeth Shaji Kiana Lim Juan Marte Dani Ashley Sosa David P. Yamane Ivy Benjenk Nivedita Prasanna Smith F. Heavner-Sullivan Prera J. Roth Banu Sivaraj Haley Fulton Madison G Herin Marissa Crum Morgan E. Fretwell Emily-Rose Zhou Christine Waller Kara Kallies Christine Waller Jonean Thorsen Alec Fitzsimmons Haley Olsen Heda R. Dapul Sourabh Verma Alan Salas Ariel Daube Michelle Korn Michelle Ramirez Logi Rajagopalan Laura Santos Orma Smalls Atul Malhotra Abdurrahman Husain Qais Zawaydeh J.H. Steuernagle Steven Q. Davis Valentina Jovic Valentina Jovic Max Masuda Amanda Hayes Katharine Nault Michael Smith William Snow Riley Liptak Hannah Durant Valerie Pendleton Alay Nanavati Risa Mrozowsk LiManoj K Gupta Franscene E. Oulds Akshay Nandavar Yuk Ming Liu Sarah Zavala Sarah Zavala Esther Shim Ronald A. Reilkoff Julia A. Heneghan Sarah Eichen Lexie Goertzen Scott Rajala Ghislaine Feussom Ben Tang Christine C. Junia Robert Lichtenberg Hasrat Sidhu Diana Espinoza Shelden Rodrigues Maria Jose Zabala Daniela Goyes Ammu Susheela Buddhi Hatharaliyadda Naveen Rameshkumar Amulya Kasireddy Genessis Maldonado Lisseth Beltran Akshata Chaugule Hassan Khan Namrata Patil Ruhi Patil Rodrigo Cartin-Ceba Ayan Sen Amanda Palacios Giyth M. Mahdi Rahul Kashyap Ognjen Gajic Vikas Bansal Aysun Tekin Amos Lal John C. O’Horo Neha N. Deo Mayank Sharma Shahraz Qamar Cory J. Kudrna Juan Pablo Domecq Garces Abigail T. La Nou Marija Bogojevic Devang Sanghavi Pramod Guru Karthik Gnanapandithan Hollie Saunders Zachary Fleissner Juan Garcia Alejandra Yu Lee Mateus Siva Naga Yarrarapu Syed Anjum Khan Juan Pablo Domecq Nitesh Kumar Jain Thoyaja Koritala Alexander Bastidas Gabriela Orellana Adriana Briceno Bierwirth Eliana Milazzo Juan Guillermo Sierra Thao Dang Amy B. Christie Dennis W. Ashley Rajani Adiga Rahul S Nanchal Paul A Bergl Jennifer L Peterson Travis Yamanaka Nicholas A. Barreras Michael Markos Anita Fareeduddin Rohan Mehta Chakradhar Venkata Miriam Engemann Annamarie Mantese Yasir Tarabichi Adam Perzynski Christine Wang Dhatri Kotekal Adriana C Briceno Bierwirth Gabriela M Orellana Gerardo Catalasan Shohana Ahmed Carlos F Matute Ahmad Hamdan Ivania Salinas Genesis Del Nogal Angel Tejada Anna Eschler Mary Hejna Emily Lewandowski Kristen Kusmierski Clare Martin Jen-Ting Chen Aluko Hope Zoe Tsagaris Elise Ruen Aram Hambardzumyan Prithvi Sendi Meghana Nadiger Balagangadhar Totapally Bhagat S. Aulakh Sandeep Tripathi Jennifer A. Bandy Lisa M. Kreps Dawn R. Bollinger Jennifer A. Bandy Roger Scott Stienecker Andre G. Melendez Tressa A. Brunner Sue M Budzon Jessica L. Heffernan Janelle M. Souder Tracy L. Miller Andrea G. Maisonneuve Roberta E. Redfern Jessica Shoemaker Jennifer Micham Lynn Kenney Gabriel Naimy Sara Utley Holly Balcer Kerry P. J. Pulver Jennifer Yehle Alicia Weeks Terra Inman Brian L. Delmonaco Anthony Franklin Mitchell Heath Antonia L. Vilella Sara B. Kutner Kacie Clark Danielle Moore Shina Menon John K McGuire Deana Rich Harry L. Anderson, III Dixy Rajkumar Ali Abunayla Jerrilyn Heiter Howard A. Zaren Stephanie J. Smith Grant C. Lewis Lauren Seames Cheryl Farlow Judy Miller Gloria Broadstreet John Lin Cindy Terrill Brock Montgomery Sydney Reyes Summer Reyes Alex Plattner Anthony Martinez Micheal Allison Aniket Mittal Rafael Ruiz Aleta Skaanland Robert Ross Umang Patel Jordesha Hodge KrunalKumar Patel Shivani Dalal Himanshu Kavani Sam Joseph Michael A. Bernstein Ian K. Goff Matthew Naftilan Amal Mathew Deborah Williams Sue Murdock Maryanne Ducey Kerianne Nelson Paul K Mohabir Connor G O’Brien Komal Dasani William Marx Ioana Amzuta Asad J. Choudhry Mohammad T. Azam Kristina L Carter Michael A Olmos Brittany M Parker Julio Quintanilla Tara A Craig Brendon J Clough Jeffrey T Jameson Neha Gupta Tracy L Jones Shonda C Ayers Amy B Harrell Dr.Brent R Brown Utpal S. Bhalala Joshua Kuehne Melinda Garcia Morgan Beebe Heather Herrera Chris Fiack Stephanie Guo May Vawer Beth Blackburn Megan Edwards Caleb Darby Kristy Page Amanda Brown Jessie McAbee Katherine A. Belden Michael Baram Devin M. Weber Rosalie DePaola Yuwei Xia Hudson Carter Aaron Tolley Mark Steele Laurie Kemble Joshua L. Denson A. Scott Gillet Margo Brown Rachael Stevens Andrew Wetherbie Kevin Tea Mathew Moore Abdurrahman Husain Atul Malhotra Qais Zawaydeh Benjamin J Sines Thomas J Bice Emily A. Vail Susannah Nicholson Rachelle B. Jonas AnnaRose E. Dement William Tang Mark DeRosa Robert E. Villarreal Rajany V. Dy Alfredo Iardino Jill Sharma Richard Czieki Julia Christopher Ryan Lacey Marwan Mashina Kushal Patel Erica C. Bjornstad Nancy M. Tofil Scott House Isabella Aldana Nikhil K. Meena Jose D. Caceres Nikhil K Meena Sarenthia M. Epps Harmeen Goraya Kelsey R. Besett Ryan James Lana Y. Abusalem Akash K. Patel Lana S Hasan Dina Gomaa Michael Goodman Devin Wakefield Anthony Spuzzillo John O. Shinn, II Azra Bihorac Tezcan Ozrazgat Baslanti George Omalay Haleh Hashemighouchani Julie S. Cupka Matthew M Ruppert Patrick W. McGonagill Colette Galet Janice Hubbard David Wang Lauren Allan Aditya Badheka Madhuradhar Chegondi Usman Nazir Garrett Rampon Jake Riggle Nathan Dismang Vicki Montgomery Janice Sullivan Sarah Morris Jennifer Nason Roger A. Alvarez Amarilys Alarcon-Calderon Marie Anne Sosa Sunita K. Mahabir Mausam J. Patel Pauline Park Andrew Admon Sinan Hanna Rishi Chanderraj Maria Pliakas Ann Wolski Jennifer Cirino Dima Dandachi Hariharan Regunath Maraya N. Camazine Grant. E. Geiger Abdoulie O. Njai Baraa M. Saad Faraaz Ali Shah Byron Chuan Sagar L. Rawal Manal Piracha Joseph E. Tonna Nicholas M. Levin Kayte Suslavich Rachel Tsolinas Zachary T. Fica Chloe R. Skidmore Renee D. Stapleton Anne E. Dixon Olivia Johnson Sara S. Ardren Stephanie Burns Anna Raymond Erika Gonyaw Kevin Hodgdon Chloe Housenger Benjamin Lin Karen McQuesten Heidi Pecott-Grimm Julie Sweet Sebastian Ventrone Nita Khandelwal T. Eoin West Ellen S. Caldwell Lara Lovelace-Macon Navya Garimella Denisse B. Dow Murtaza Akhter Rania Abdul Rahman Mary Mulrow Erin M. Wilfong Kelsi Vela Ashish K. Khanna Lynne Harris Bruce Cusson Jacob Fowler David Vaneenenaam Glen McKinney Imoh Udoh Kathleen Johnson Patrick G. Lyons Andrew P Michelson Sara S. Haluf Lauren M. Lynch Nguyet M. Nguyen Aaron Steinberg Nicholas Braus Vishwanath Pattan Jessica Papke Ismail Jimada Nida Mhid Samuel Chakola
author_facet	Sandeep Tripathi, MD, MS Imran A. Sayed, MD Heda Dapul, MD Jeremy S. McGarvey, MS Jennifer A. Bandy, RN Karen Boman, BS Vishakha K. Kumar, MD, MBA Vikas Bansal, MBBS, MPH Lynn Retford, CAE Sreekanth Cheruku, MD, MPH Margit Kaufman, MD, FASA Smith F. Heavner, MS, RN Valerie C. Danesh, PhD, RN Catherine A. St. Hill, DVM, PhD Ashish K. Khanna, MD Utpal Bhalala, MD Rahul Kashyap, MBBS, MBA Ognjen Gajic, MD, MS Allan J. Walkey, MD, MS Katja M. Gist, DO, MSc for The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group Jean-Baptiste Mesland Pierre Henin Hélène Petre Isabelle Buelens Anne-Catherine Gerard Philippe Clevenbergh Rolando Claure-Del Granado Jose A. Mercado Esdenka Vega-Terrazas Maria F. Iturricha-Caceres Ruben Garza Eric Chu Victoria Chan Oscar Y Gavidia Felipe Pachon Yeimy A Sanchez Mohamed El Kassas Mohamed Badr Ahmed Tawheed Ahmed Tawheed Hend Yahia Sierra-Hoffman Fernando Valerio Oscar Diaz Jose Luis Ramos Coello Guillermo Perez Ana Karen Vallecillo Lizardo Gabina María Reyes Guillen Helin Archaga Soto Mradul Kumar Daga Munisha Agarwal Ishan Rohtagi Anusha Cherian Sreejith Parameswaran Magesh Parthiban Menu Priya A. Girish Vadgaonkar Rekha Ediga Shilpa Basety Shwetha Dammareddy Phani Sreeharsha Kasumalla Sridhar Papani Mahesh Kamuram Smitha S. Segu Tuhin Chakraborty Epcebha Joyce Umamaheswara Raju Janaki Manduva Naresh Kolakani Shreeja Sripathi Sheetal Chaitanya Surapaneni Krishna Mohan Ekambaram Jyothisree Kamlesh Kumar Agrawal Vijendra Baghel Kirti Kumar Patel Nooshin Dalili Mohsen Nafa Sandeep Tripathi Yuki Itagaki Akira Kodate Reina Suzuki Akira Kodate Yuki Takahashi Koyo Moriki Michihito Kyo Reina Suzuki Masamitsu Sanui Sho Horikita Wataru Matsuda Reina Suzuki Shu Tahara Mineji Hayakawa Kunihiko Maekawa Takuya Shiga Yudai Iwasaki Abdulrahman AlFares Rene Rodriguez-Gutierrez Jose Gerardo Gonzalez-Gonzalez Alejandro Salcido-Montenegro Adrian Camacho-Ortiz Fatimah Hassan-Hanga Hadiza Galadanci Abubakar Shehu Gezawa Halima M. S. Kabara Taiwo Gboluwaga Amole Halima Kabir Dalha Gwarzo Haliru, Abdullahi S Ibrahim Muhammad Sohaib Asghar Mashaal Syed Syed Anosh Ali Naqvi Igor Borisovich Zabolotskikh Konstantin Dmitrievich Zybin Sergey Vasilevich Sinkov Tatiana Sergeevna Musaeva Marwa Ridha Amer Mohammed Abdullah Bawazeer Talal I. Dahhan Eiad Kseibi Abid Shahzad Butt Syed Moazzum Khurshid Muath Rabee Mohammed Abujazar Razan Alghunaim Maal Abualkhair Abeer Turki AlFirm Eiad Kseibi Syed Moazzum Khurshid Muath Rabee Mohammed Abujazar Razan Alghunaim Razan K Alamoudi Hassan M. AlSharif Sarah A. Almazwaghi Mohammed S Elsakran Mohamed A Aid Mouaz A Darwich Omnia M Hagag Salah A Ali Alona rocacorba Kathrine Supeña Efren Ray Juane Jenalyn Medina Jowany Baduria Mohammed A Almazyad Mohammed I Alarifi Jara M Macarambon Ahmad Abdullah Bukhari Hussain A. Albahrani Kazi N Asfina Kaltham M Aldossary Predrag D Stevanovic Dejan S Stojakov Duska K Ignjatovic Suzana C Bojic Marina M Bobos Irina B Nenadic Milica S Zaric Marko D Djuric Vladimir R Djukic Bojan Kovacevic Jovana Bojicic Marija Zdravkovic Zoran Todorovic Viseslav Popadic Slobodan Klasnja Santiago Y. Teruel Belen C. Martin Santiago Y. Teruel Himat Sulaimonov Firuza Khudonazarova Nabi Bakhtibekov Nekruz Jamshedov Uluhan Sili Huseyin Bilgin Pinar Ay Varsha P Gharpure Usman Raheemi Kenneth W. Dodd Nicholas Goodmanson Kathleen Hesse Paige Bird Chauncey Weinert Nathan Schoenrade Abdulrahman Altaher Esmael Mayar Matthew Aronson Tyler Cooper Monica Logan Brianna Miner Gisele Papo Eric M. Siegal Phyllis Runningen Catherine A. St. Hill Roman R. Melamed David M. Tierney Love A. Patel Vino S. Raj Barite U. Dawud Narayana Mazumder Abbey Sidebottom Alena M. Guenther Benjamin D. Krehbiel Nova J. Schmitz Stacy L. Jepsen Abhijit A Raval Andrea Franks Katherine Irby Ronald C. Sanders, Jr. Glenda Hefley Anmol Kharbanda Sunil Jhajhria Zachary Fyffe Stephen Capizzi Bethany Alicie Martha Green Lori Crockarell Amelia Drennan Kathleen Dubuque Tonya Fambrough Nikole Gasaway Briana Krantz Peiman Nebi Jan Orga Margaret Serfass Alina Simion Kimberly Warren Cassie Wheeler CJ Woolman Andrew S. Moyer George M. Verghese Andrea Sikora Newsome Christy C. Forehand Rebecca Bruning Timothy W. Jones Moldovan Sabov Fatema Zaidi Fiona Tissavirasingham Dhatri Malipeddi Jarrod M Mosier Karen Lutrick Beth Salvagio Campbell Cathleen Wilson Patrick Rivers Jonathan Brinks Mokenge Ndiva Mongoh Boris Gilson Donna Lee Armaignac Don Parris Maria Pilar Zuniga Ilea Vargas Viviana Boronat Anneka Hutton Navneet Kaur Prashank Neupane Nohemi Sadule-Rios Lourdes M. Rojas Aashish Neupane Priscilla Rivera Carlos Valle Carlos Gregory Vincent Mahesh Amin Mary E Schelle Amanda Steadham Christopher M Howard Cameron McBride Jocelyn Abraham Orlando Garner Katherine Richards Keegan Collins Preethi Antony Sindhu Mathew Valerie C. Danesh Gueorgui Dubrocq Amber L. Davis Marissa J Hammers ill M. McGahey Amanda C. Farris Elisa Priest Robyn Korsmo Lorie Fares Kathy Skiles Susan M. Shor Kenya Burns Corrie A Dowell Melody Flores Lindsay Newman Debora A Wilk Jason Ettlinger Jaccallene Bomar Himani Darji Alejandro Arroliga Alejandro C Arroliga Corrie A. Dowell Gabriela Hope Conzales Melody Flores Lindsay Newman Debora A. Wilk Jason Ettlinger Himani Darji Jaccallene Bomar Paras B. Khandhar Elizabeth Kring Valerie M. Banner-Goodspeed Somnath Bose Lauren E. Kelly Melisa Joseph Marie McGourty Krystal Capers Benjamin Hoenig Maria C. Karamourtopoulos Anica C. Law Elias N. Baedorf Kassis Allan J. Walkey Sushrut S. Waikar Michael A. Garcia Mia Colona Zoe Kibbelaar Michael Leong Daniel Wallman Kanupriya Soni Jennifer Maccarone Joshua Gilman Ycar Devis Joseph Chung Munizay Paracha David N. Lumelsky Madeline DiLorenzo Najla Abdurrahman Shelsey Johnson Andrew M. Hersh Stephanie L Wachs Brittany S. Swigger Stephanie L Wachs Lauren A. Sattler Michael N. Moulton Kimberly Zammit J Patrick William McGrath Maya Loeffler R Chilbert Aaron S. Miller Edwin L. Anderson Rosemary Nagy Ravali R. Inja Raghavendra Tirupathi Alymer Tang Arshad Safi Cindy Green Jackie Newell Rayan E. Ihle Shelda A. Martin Elaine A. Davis Katja M. Gist Imran A Sayed John Brinton Larisa Strom Kathleen Chiotos Allison M. Blatz Giyoung Lee Ryan H. Burnett Guy I. Sydney Danielle M. Traynor Karissa Nauert Annika Gonzalez Mariel Bagley Anita Santpurkar Salim Surani Joshua White Aftab Khan Rahul Dhahwal Sreekanth Cheruku Farzin Ahmed Christopher Deonarine Ashley Jones Mohammad-Ali Shaikh David Preston Jeanette Chin Vidula Vachharajani Abhijit Duggal Prabalini Rajendram Omar Mehkri Siddharth Dugar Michelle Biehl Gretchen Sacha Stuart Houltham Alexander King Kiran Ashok Bryan Poynter Mary Beukemann Richard Rice Susan Gole Valerie Shaner Adarsh Conjeevaram Michelle Ferrari Narendrakumar Alappan Steven Minear Jaime Hernandez-Montfort Syed Sohaib Nasim Ravi Sunderkrishnan Debasis Sahoo Patrick S. Milligan Sandeep K. Gupta Joy M. Koglin Regina Gibson Lana Johnson Felicia Preston Crimson Scott Bethany Nungester Steven K. Daugherty Sam Atkinson Kelly Shrimpton Sidney Ontai Brian Contreras Uzoma Obinwanko Nneka Amamasi Amir Sharafi Sarah Lee Zahia Esber Chetna Jinjvadia Kimberly Welker Francis M. Maguire Jessica Timmer Raquel R Bartz Vijay Krishnamoorthy Bryan Kraft Aaron Pulsipher Eugene Friedman Sachin Mehta Margit Kaufman Gregg Lobel Nisha Gandhi Amr Abdelaty Elizabeth Shaji Kiana Lim Juan Marte Dani Ashley Sosa David P. Yamane Ivy Benjenk Nivedita Prasanna Smith F. Heavner-Sullivan Prera J. Roth Banu Sivaraj Haley Fulton Madison G Herin Marissa Crum Morgan E. Fretwell Emily-Rose Zhou Christine Waller Kara Kallies Christine Waller Jonean Thorsen Alec Fitzsimmons Haley Olsen Heda R. Dapul Sourabh Verma Alan Salas Ariel Daube Michelle Korn Michelle Ramirez Logi Rajagopalan Laura Santos Orma Smalls Atul Malhotra Abdurrahman Husain Qais Zawaydeh J.H. Steuernagle Steven Q. Davis Valentina Jovic Valentina Jovic Max Masuda Amanda Hayes Katharine Nault Michael Smith William Snow Riley Liptak Hannah Durant Valerie Pendleton Alay Nanavati Risa Mrozowsk LiManoj K Gupta Franscene E. Oulds Akshay Nandavar Yuk Ming Liu Sarah Zavala Sarah Zavala Esther Shim Ronald A. Reilkoff Julia A. Heneghan Sarah Eichen Lexie Goertzen Scott Rajala Ghislaine Feussom Ben Tang Christine C. Junia Robert Lichtenberg Hasrat Sidhu Diana Espinoza Shelden Rodrigues Maria Jose Zabala Daniela Goyes Ammu Susheela Buddhi Hatharaliyadda Naveen Rameshkumar Amulya Kasireddy Genessis Maldonado Lisseth Beltran Akshata Chaugule Hassan Khan Namrata Patil Ruhi Patil Rodrigo Cartin-Ceba Ayan Sen Amanda Palacios Giyth M. Mahdi Rahul Kashyap Ognjen Gajic Vikas Bansal Aysun Tekin Amos Lal John C. O’Horo Neha N. Deo Mayank Sharma Shahraz Qamar Cory J. Kudrna Juan Pablo Domecq Garces Abigail T. La Nou Marija Bogojevic Devang Sanghavi Pramod Guru Karthik Gnanapandithan Hollie Saunders Zachary Fleissner Juan Garcia Alejandra Yu Lee Mateus Siva Naga Yarrarapu Syed Anjum Khan Juan Pablo Domecq Nitesh Kumar Jain Thoyaja Koritala Alexander Bastidas Gabriela Orellana Adriana Briceno Bierwirth Eliana Milazzo Juan Guillermo Sierra Thao Dang Amy B. Christie Dennis W. Ashley Rajani Adiga Rahul S Nanchal Paul A Bergl Jennifer L Peterson Travis Yamanaka Nicholas A. Barreras Michael Markos Anita Fareeduddin Rohan Mehta Chakradhar Venkata Miriam Engemann Annamarie Mantese Yasir Tarabichi Adam Perzynski Christine Wang Dhatri Kotekal Adriana C Briceno Bierwirth Gabriela M Orellana Gerardo Catalasan Shohana Ahmed Carlos F Matute Ahmad Hamdan Ivania Salinas Genesis Del Nogal Angel Tejada Anna Eschler Mary Hejna Emily Lewandowski Kristen Kusmierski Clare Martin Jen-Ting Chen Aluko Hope Zoe Tsagaris Elise Ruen Aram Hambardzumyan Prithvi Sendi Meghana Nadiger Balagangadhar Totapally Bhagat S. Aulakh Sandeep Tripathi Jennifer A. Bandy Lisa M. Kreps Dawn R. Bollinger Jennifer A. Bandy Roger Scott Stienecker Andre G. Melendez Tressa A. Brunner Sue M Budzon Jessica L. Heffernan Janelle M. Souder Tracy L. Miller Andrea G. Maisonneuve Roberta E. Redfern Jessica Shoemaker Jennifer Micham Lynn Kenney Gabriel Naimy Sara Utley Holly Balcer Kerry P. J. Pulver Jennifer Yehle Alicia Weeks Terra Inman Brian L. Delmonaco Anthony Franklin Mitchell Heath Antonia L. Vilella Sara B. Kutner Kacie Clark Danielle Moore Shina Menon John K McGuire Deana Rich Harry L. Anderson, III Dixy Rajkumar Ali Abunayla Jerrilyn Heiter Howard A. Zaren Stephanie J. Smith Grant C. Lewis Lauren Seames Cheryl Farlow Judy Miller Gloria Broadstreet John Lin Cindy Terrill Brock Montgomery Sydney Reyes Summer Reyes Alex Plattner Anthony Martinez Micheal Allison Aniket Mittal Rafael Ruiz Aleta Skaanland Robert Ross Umang Patel Jordesha Hodge KrunalKumar Patel Shivani Dalal Himanshu Kavani Sam Joseph Michael A. Bernstein Ian K. Goff Matthew Naftilan Amal Mathew Deborah Williams Sue Murdock Maryanne Ducey Kerianne Nelson Paul K Mohabir Connor G O’Brien Komal Dasani William Marx Ioana Amzuta Asad J. Choudhry Mohammad T. 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Meena Jose D. Caceres Nikhil K Meena Sarenthia M. Epps Harmeen Goraya Kelsey R. Besett Ryan James Lana Y. Abusalem Akash K. Patel Lana S Hasan Dina Gomaa Michael Goodman Devin Wakefield Anthony Spuzzillo John O. Shinn, II Azra Bihorac Tezcan Ozrazgat Baslanti George Omalay Haleh Hashemighouchani Julie S. Cupka Matthew M Ruppert Patrick W. McGonagill Colette Galet Janice Hubbard David Wang Lauren Allan Aditya Badheka Madhuradhar Chegondi Usman Nazir Garrett Rampon Jake Riggle Nathan Dismang Vicki Montgomery Janice Sullivan Sarah Morris Jennifer Nason Roger A. Alvarez Amarilys Alarcon-Calderon Marie Anne Sosa Sunita K. Mahabir Mausam J. Patel Pauline Park Andrew Admon Sinan Hanna Rishi Chanderraj Maria Pliakas Ann Wolski Jennifer Cirino Dima Dandachi Hariharan Regunath Maraya N. Camazine Grant. E. Geiger Abdoulie O. Njai Baraa M. Saad Faraaz Ali Shah Byron Chuan Sagar L. Rawal Manal Piracha Joseph E. Tonna Nicholas M. Levin Kayte Suslavich Rachel Tsolinas Zachary T. Fica Chloe R. Skidmore Renee D. Stapleton Anne E. Dixon Olivia Johnson Sara S. Ardren Stephanie Burns Anna Raymond Erika Gonyaw Kevin Hodgdon Chloe Housenger Benjamin Lin Karen McQuesten Heidi Pecott-Grimm Julie Sweet Sebastian Ventrone Nita Khandelwal T. Eoin West Ellen S. Caldwell Lara Lovelace-Macon Navya Garimella Denisse B. Dow Murtaza Akhter Rania Abdul Rahman Mary Mulrow Erin M. Wilfong Kelsi Vela Ashish K. Khanna Lynne Harris Bruce Cusson Jacob Fowler David Vaneenenaam Glen McKinney Imoh Udoh Kathleen Johnson Patrick G. Lyons Andrew P Michelson Sara S. Haluf Lauren M. Lynch Nguyet M. Nguyen Aaron Steinberg Nicholas Braus Vishwanath Pattan Jessica Papke Ismail Jimada Nida Mhid Samuel Chakola
author_sort	Sandeep Tripathi, MD, MS
title	Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry
title_short	Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry
title_full	Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry
title_fullStr	Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry
title_full_unstemmed	Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry
title_sort	risk factors for critical coronavirus disease 2019 and mortality in hospitalized young adults: an analysis of the society of critical care medicine discovery viral infection and respiratory illness universal study (virus) coronavirus disease 2019 registry
publisher	Wolters Kluwer
publishDate	2021
url	https://doaj.org/article/ae0fb2090d944883bab4c102a169e8a4
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spelling	oai:doaj.org-article:ae0fb2090d944883bab4c102a169e8a42021-11-25T07:55:47ZRisk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry2639-802810.1097/CCE.0000000000000514https://doaj.org/article/ae0fb2090d944883bab4c102a169e8a42021-08-01T00:00:00Zhttp://journals.lww.com/10.1097/CCE.0000000000000514https://doaj.org/toc/2639-8028IMPORTANCE:. Even with its proclivity for older age, coronavirus disease 2019 has been shown to affect all age groups. However, there remains a lack of research focused primarily on the young adult population. OBJECTIVES:. To describe the epidemiology and outcomes of coronavirus disease 2019 and identify the risk factors associated with critical illness and mortality in hospitalized young adults. DESIGN, SETTINGS, AND PARTICIPANTS:. A retrospective cohort study of the Society of Critical Care Medicine’s Viral Infection and Respiratory Illness Universal Study registry. Patients 18–40 years old, hospitalized from coronavirus disease 2019 from March 2020 to April 2021, were included in the analysis. MAIN OUTCOMES AND MEASURES:. Critical illness was defined as a composite of mortality and 21 predefined interventions and complications. Multivariable logistic regression was used to assess associations with critical illness and mortality. RESULTS:. Data from 4,005 patients (152 centers, 19 countries, 18.6% non-U.S. patients) were analyzed. The median age was 32 years (interquartile range, 27–37 yr); 51% were female, 29.4% Hispanic, and 42.9% had obesity. Most patients (63.2%) had comorbidities, the most common being hypertension (14.5%) and diabetes (13.7%). Hospital and ICU mortality were 3.2% (129/4,005) and 8.3% (109/1,313), respectively. Critical illness occurred in 25% (n = 996), and 34.3% (n = 1,376) were admitted to the ICU. Older age (p = 0.03), male sex (adjusted odds ratio, 1.83 [95% CI, 1.2–2.6]), and obesity (adjusted odds ratio, 1.6 [95% CI, 1.1–2.4]) were associated with hospital mortality. In addition to the above factors, the presence of any comorbidity was associated with critical illness from coronavirus disease 2019. Multiple sensitivity analyses, including analysis with U.S. patients only and patients admitted to high-volume sites, showed similar risk factors. CONCLUSIONS:. Among hospitalized young adults, obese males with comorbidities are at higher risk of developing critical illness or dying from coronavirus disease 2019.Sandeep Tripathi, MD, MSImran A. Sayed, MDHeda Dapul, MDJeremy S. McGarvey, MSJennifer A. Bandy, RNKaren Boman, BSVishakha K. Kumar, MD, MBAVikas Bansal, MBBS, MPHLynn Retford, CAESreekanth Cheruku, MD, MPHMargit Kaufman, MD, FASASmith F. Heavner, MS, RNValerie C. Danesh, PhD, RNCatherine A. St. Hill, DVM, PhDAshish K. Khanna, MDUtpal Bhalala, MDRahul Kashyap, MBBS, MBAOgnjen Gajic, MD, MSAllan J. Walkey, MD, MSKatja M. Gist, DO, MScfor The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator GroupJean-Baptiste MeslandPierre HeninHélène PetreIsabelle BuelensAnne-Catherine GerardPhilippe ClevenberghRolando Claure-Del GranadoJose A. MercadoEsdenka Vega-TerrazasMaria F. Iturricha-CaceresRuben GarzaEric ChuVictoria ChanOscar Y GavidiaFelipe PachonYeimy A SanchezMohamed El KassasMohamed BadrAhmed TawheedAhmed TawheedHend YahiaSierra-HoffmanFernando ValerioOscar DiazJose Luis Ramos CoelloGuillermo PerezAna Karen Vallecillo LizardoGabina María Reyes GuillenHelin Archaga SotoMradul Kumar DagaMunisha AgarwalIshan RohtagiAnusha CherianSreejith ParameswaranMagesh ParthibanMenu Priya A.Girish VadgaonkarRekha EdigaShilpa BasetyShwetha DammareddyPhani Sreeharsha KasumallaSridhar PapaniMahesh KamuramSmitha S. SeguTuhin ChakrabortyEpcebha JoyceUmamaheswara RajuJanaki ManduvaNaresh KolakaniShreeja SripathiSheetal ChaitanyaSurapaneni Krishna MohanEkambaram JyothisreeKamlesh Kumar AgrawalVijendra BaghelKirti Kumar PatelNooshin DaliliMohsen NafaSandeep TripathiYuki ItagakiAkira KodateReina SuzukiAkira KodateYuki TakahashiKoyo MorikiMichihito KyoReina SuzukiMasamitsu SanuiSho HorikitaWataru MatsudaReina SuzukiShu TaharaMineji HayakawaKunihiko MaekawaTakuya ShigaYudai IwasakiAbdulrahman AlFaresRene Rodriguez-GutierrezJose Gerardo Gonzalez-GonzalezAlejandro Salcido-MontenegroAdrian Camacho-OrtizFatimah Hassan-HangaHadiza GaladanciAbubakar Shehu GezawaHalima M. S. KabaraTaiwo Gboluwaga AmoleHalima KabirDalha GwarzoHaliru, Abdullahi S IbrahimMuhammad Sohaib AsgharMashaal SyedSyed Anosh Ali NaqviIgor Borisovich ZabolotskikhKonstantin Dmitrievich ZybinSergey Vasilevich SinkovTatiana Sergeevna MusaevaMarwa Ridha AmerMohammed Abdullah BawazeerTalal I. DahhanEiad KseibiAbid Shahzad ButtSyed Moazzum KhurshidMuath RabeeMohammed AbujazarRazan AlghunaimMaal AbualkhairAbeer Turki AlFirmEiad KseibiSyed Moazzum KhurshidMuath RabeeMohammed AbujazarRazan AlghunaimRazan K AlamoudiHassan M. AlSharifSarah A. AlmazwaghiMohammed S ElsakranMohamed A AidMouaz A DarwichOmnia M HagagSalah A AliAlona rocacorbaKathrine SupeñaEfren Ray JuaneJenalyn MedinaJowany BaduriaMohammed A AlmazyadMohammed I AlarifiJara M MacarambonAhmad Abdullah BukhariHussain A. AlbahraniKazi N AsfinaKaltham M AldossaryPredrag D StevanovicDejan S StojakovDuska K IgnjatovicSuzana C BojicMarina M BobosIrina B NenadicMilica S ZaricMarko D DjuricVladimir R DjukicBojan KovacevicJovana BojicicMarija ZdravkovicZoran TodorovicViseslav PopadicSlobodan KlasnjaSantiago Y. TeruelBelen C. MartinSantiago Y. TeruelHimat SulaimonovFiruza KhudonazarovaNabi BakhtibekovNekruz JamshedovUluhan SiliHuseyin BilginPinar AyVarsha P GharpureUsman RaheemiKenneth W. DoddNicholas GoodmansonKathleen HessePaige BirdChauncey WeinertNathan SchoenradeAbdulrahman AltaherEsmael MayarMatthew AronsonTyler CooperMonica LoganBrianna MinerGisele PapoEric M. SiegalPhyllis RunningenCatherine A. St. HillRoman R. MelamedDavid M. TierneyLove A. PatelVino S. RajBarite U. DawudNarayana MazumderAbbey SidebottomAlena M. GuentherBenjamin D. KrehbielNova J. SchmitzStacy L. JepsenAbhijit A RavalAndrea FranksKatherine IrbyRonald C. Sanders, Jr.Glenda HefleyAnmol KharbandaSunil JhajhriaZachary FyffeStephen CapizziBethany AlicieMartha GreenLori CrockarellAmelia DrennanKathleen DubuqueTonya FambroughNikole GasawayBriana KrantzPeiman NebiJan OrgaMargaret SerfassAlina SimionKimberly WarrenCassie WheelerCJ WoolmanAndrew S. MoyerGeorge M. VergheseAndrea Sikora NewsomeChristy C. ForehandRebecca BruningTimothy W. JonesMoldovan SabovFatema ZaidiFiona TissavirasinghamDhatri MalipeddiJarrod M MosierKaren LutrickBeth Salvagio CampbellCathleen WilsonPatrick RiversJonathan BrinksMokenge Ndiva MongohBoris GilsonDonna Lee ArmaignacDon ParrisMaria Pilar ZunigaIlea VargasViviana BoronatAnneka HuttonNavneet KaurPrashank NeupaneNohemi Sadule-RiosLourdes M. RojasAashish NeupanePriscilla RiveraCarlos Valle CarlosGregory VincentMahesh AminMary E SchelleAmanda SteadhamChristopher M HowardCameron McBrideJocelyn AbrahamOrlando GarnerKatherine RichardsKeegan CollinsPreethi AntonySindhu MathewValerie C. DaneshGueorgui DubrocqAmber L. DavisMarissa J Hammersill M. McGaheyAmanda C. FarrisElisa PriestRobyn KorsmoLorie FaresKathy SkilesSusan M. ShorKenya BurnsCorrie A DowellMelody FloresLindsay NewmanDebora A WilkJason EttlingerJaccallene BomarHimani DarjiAlejandro ArroligaAlejandro C ArroligaCorrie A. DowellGabriela Hope ConzalesMelody FloresLindsay NewmanDebora A. WilkJason EttlingerHimani DarjiJaccallene BomarParas B. KhandharElizabeth KringValerie M. Banner-GoodspeedSomnath BoseLauren E. KellyMelisa JosephMarie McGourtyKrystal CapersBenjamin HoenigMaria C. KaramourtopoulosAnica C. LawElias N. Baedorf KassisAllan J. WalkeySushrut S. WaikarMichael A. GarciaMia ColonaZoe KibbelaarMichael LeongDaniel WallmanKanupriya SoniJennifer MaccaroneJoshua GilmanYcar DevisJoseph ChungMunizay ParachaDavid N. LumelskyMadeline DiLorenzoNajla AbdurrahmanShelsey JohnsonAndrew M. HershStephanie L WachsBrittany S. SwiggerStephanie L WachsLauren A. SattlerMichael N. MoultonKimberly ZammitJ PatrickWilliam McGrathMaya LoefflerR ChilbertAaron S. MillerEdwin L. AndersonRosemary NagyRavali R. InjaRaghavendra TirupathiAlymer TangArshad SafiCindy GreenJackie NewellRayan E. IhleShelda A. MartinElaine A. DavisKatja M. GistImran A SayedJohn BrintonLarisa StromKathleen ChiotosAllison M. BlatzGiyoung LeeRyan H. BurnettGuy I. SydneyDanielle M. TraynorKarissa NauertAnnika GonzalezMariel BagleyAnita SantpurkarSalim SuraniJoshua WhiteAftab KhanRahul DhahwalSreekanth CherukuFarzin AhmedChristopher DeonarineAshley JonesMohammad-Ali ShaikhDavid PrestonJeanette ChinVidula VachharajaniAbhijit DuggalPrabalini RajendramOmar MehkriSiddharth DugarMichelle BiehlGretchen SachaStuart HoulthamAlexander KingKiran AshokBryan PoynterMary BeukemannRichard RiceSusan GoleValerie ShanerAdarsh ConjeevaramMichelle FerrariNarendrakumar AlappanSteven MinearJaime Hernandez-MontfortSyed Sohaib NasimRavi SunderkrishnanDebasis SahooPatrick S. MilliganSandeep K. GuptaJoy M. KoglinRegina GibsonLana JohnsonFelicia PrestonCrimson ScottBethany NungesterSteven K. DaughertySam AtkinsonKelly ShrimptonSidney OntaiBrian ContrerasUzoma ObinwankoNneka AmamasiAmir SharafiSarah LeeZahia EsberChetna JinjvadiaKimberly WelkerFrancis M. 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HeneghanSarah EichenLexie GoertzenScott RajalaGhislaine FeussomBen TangChristine C. JuniaRobert LichtenbergHasrat SidhuDiana EspinozaShelden RodriguesMaria Jose ZabalaDaniela GoyesAmmu SusheelaBuddhi HatharaliyaddaNaveen RameshkumarAmulya KasireddyGenessis MaldonadoLisseth BeltranAkshata ChauguleHassan KhanNamrata PatilRuhi PatilRodrigo Cartin-CebaAyan SenAmanda PalaciosGiyth M. MahdiRahul KashyapOgnjen GajicVikas BansalAysun TekinAmos LalJohn C. O’HoroNeha N. DeoMayank SharmaShahraz QamarCory J. KudrnaJuan Pablo Domecq GarcesAbigail T. La NouMarija BogojevicDevang SanghaviPramod GuruKarthik GnanapandithanHollie SaundersZachary FleissnerJuan GarciaAlejandra Yu Lee MateusSiva Naga YarrarapuSyed Anjum KhanJuan Pablo DomecqNitesh Kumar JainThoyaja KoritalaAlexander BastidasGabriela OrellanaAdriana Briceno BierwirthEliana MilazzoJuan Guillermo SierraThao DangAmy B. ChristieDennis W. AshleyRajani AdigaRahul S NanchalPaul A BerglJennifer L PetersonTravis YamanakaNicholas A. BarrerasMichael MarkosAnita FareeduddinRohan MehtaChakradhar VenkataMiriam EngemannAnnamarie ManteseYasir TarabichiAdam PerzynskiChristine WangDhatri KotekalAdriana C Briceno BierwirthGabriela M OrellanaGerardo CatalasanShohana AhmedCarlos F MatuteAhmad HamdanIvania SalinasGenesis Del NogalAngel TejadaAnna EschlerMary HejnaEmily LewandowskiKristen KusmierskiClare MartinJen-Ting ChenAluko HopeZoe TsagarisElise RuenAram HambardzumyanPrithvi SendiMeghana NadigerBalagangadhar TotapallyBhagat S. AulakhSandeep TripathiJennifer A. BandyLisa M. KrepsDawn R. BollingerJennifer A. BandyRoger Scott StieneckerAndre G. MelendezTressa A. BrunnerSue M BudzonJessica L. HeffernanJanelle M. SouderTracy L. MillerAndrea G. MaisonneuveRoberta E. RedfernJessica ShoemakerJennifer MichamLynn KenneyGabriel NaimySara UtleyHolly BalcerKerry P. J. PulverJennifer YehleAlicia WeeksTerra InmanBrian L. DelmonacoAnthony FranklinMitchell HeathAntonia L. VilellaSara B. 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Shinn, IIAzra BihoracTezcan Ozrazgat BaslantiGeorge OmalayHaleh HashemighouchaniJulie S. CupkaMatthew M RuppertPatrick W. McGonagillColette GaletJanice HubbardDavid WangLauren AllanAditya BadhekaMadhuradhar ChegondiUsman NazirGarrett RamponJake RiggleNathan DismangVicki MontgomeryJanice SullivanSarah MorrisJennifer NasonRoger A. AlvarezAmarilys Alarcon-CalderonMarie Anne SosaSunita K. MahabirMausam J. PatelPauline ParkAndrew AdmonSinan HannaRishi ChanderrajMaria PliakasAnn WolskiJennifer CirinoDima DandachiHariharan RegunathMaraya N. CamazineGrant. E. GeigerAbdoulie O. NjaiBaraa M. SaadFaraaz Ali ShahByron ChuanSagar L. RawalManal PirachaJoseph E. TonnaNicholas M. LevinKayte SuslavichRachel TsolinasZachary T. FicaChloe R. SkidmoreRenee D. StapletonAnne E. DixonOlivia JohnsonSara S. ArdrenStephanie BurnsAnna RaymondErika GonyawKevin HodgdonChloe HousengerBenjamin LinKaren McQuestenHeidi Pecott-GrimmJulie SweetSebastian VentroneNita KhandelwalT. Eoin WestEllen S. CaldwellLara Lovelace-MaconNavya GarimellaDenisse B. DowMurtaza AkhterRania Abdul RahmanMary MulrowErin M. WilfongKelsi VelaAshish K. KhannaLynne HarrisBruce CussonJacob FowlerDavid VaneenenaamGlen McKinneyImoh UdohKathleen JohnsonPatrick G. LyonsAndrew P MichelsonSara S. HalufLauren M. LynchNguyet M. NguyenAaron SteinbergNicholas BrausVishwanath PattanJessica PapkeIsmail JimadaNida MhidSamuel ChakolaWolters KluwerarticleMedical emergencies. Critical care. Intensive care. First aidRC86-88.9ENCritical Care Explorations, Vol 3, Iss 8, p e0514 (2021)

Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry

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