Projections of the Mouse Primary Visual Cortex

Lesion or damage to the primary visual cortex (V1) results in a profound loss of visual perception in humans. Similarly, in mice, optogenetic silencing of V1 profoundly impairs discrimination of orientated gratings. V1 is thought to have such a critical role in perception in part due to its position...

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Autor principal:	Arbora Resulaj
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	primary visual cortex (V1) projections mouse synaptic connectivity behavior Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/ae1860bf64264f71917c53f7b4417fd5
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id	oai:doaj.org-article:ae1860bf64264f71917c53f7b4417fd5
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spelling	oai:doaj.org-article:ae1860bf64264f71917c53f7b4417fd52021-11-19T12:56:11ZProjections of the Mouse Primary Visual Cortex1662-511010.3389/fncir.2021.751331https://doaj.org/article/ae1860bf64264f71917c53f7b4417fd52021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fncir.2021.751331/fullhttps://doaj.org/toc/1662-5110Lesion or damage to the primary visual cortex (V1) results in a profound loss of visual perception in humans. Similarly, in mice, optogenetic silencing of V1 profoundly impairs discrimination of orientated gratings. V1 is thought to have such a critical role in perception in part due to its position in the visual processing hierarchy. It is the first brain area in the neocortex to receive visual input, and it distributes this information to more than 18 brain areas. Here I review recent advances in our understanding of the organization and function of the V1 projections in the mouse. This progress is in part due to new anatomical and viral techniques that allow for efficient labeling of projection neurons. In the final part of the review, I conclude by highlighting challenges and opportunities for future research.Arbora ResulajArbora ResulajFrontiers Media S.A.articleprimary visual cortex (V1)projectionsmousesynaptic connectivitybehaviorNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENFrontiers in Neural Circuits, Vol 15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	primary visual cortex (V1) projections mouse synaptic connectivity behavior Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	primary visual cortex (V1) projections mouse synaptic connectivity behavior Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Arbora Resulaj Arbora Resulaj Projections of the Mouse Primary Visual Cortex
description	Lesion or damage to the primary visual cortex (V1) results in a profound loss of visual perception in humans. Similarly, in mice, optogenetic silencing of V1 profoundly impairs discrimination of orientated gratings. V1 is thought to have such a critical role in perception in part due to its position in the visual processing hierarchy. It is the first brain area in the neocortex to receive visual input, and it distributes this information to more than 18 brain areas. Here I review recent advances in our understanding of the organization and function of the V1 projections in the mouse. This progress is in part due to new anatomical and viral techniques that allow for efficient labeling of projection neurons. In the final part of the review, I conclude by highlighting challenges and opportunities for future research.
format	article
author	Arbora Resulaj Arbora Resulaj
author_facet	Arbora Resulaj Arbora Resulaj
author_sort	Arbora Resulaj
title	Projections of the Mouse Primary Visual Cortex
title_short	Projections of the Mouse Primary Visual Cortex
title_full	Projections of the Mouse Primary Visual Cortex
title_fullStr	Projections of the Mouse Primary Visual Cortex
title_full_unstemmed	Projections of the Mouse Primary Visual Cortex
title_sort	projections of the mouse primary visual cortex
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/ae1860bf64264f71917c53f7b4417fd5
work_keys_str_mv	AT arboraresulaj projectionsofthemouseprimaryvisualcortex AT arboraresulaj projectionsofthemouseprimaryvisualcortex
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Projections of the Mouse Primary Visual Cortex

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