Pan-cancer analysis of SETD2 mutation and its association with the efficacy of immunotherapy

Abstract Histone methyltransferase SETD2 plays a critical role in maintaining genomic integrity and stability. Here, we investigated the characteristics of SETD2 somatic mutation in the cancer genome atlas pan-cancer cohort. Our data revealed that, compared with SETD2 nonmutant patients, SETD2 mutan...

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Auteurs principaux: Mingdong Lu, Bin Zhao, Mengshan Liu, Le Wu, Yingying Li, Yingna Zhai, Xian Shen
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/ae21fcd0412c44bda93ebc0cd806c6e7
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