P50, the small subunit of DNA polymerase delta, is required for mediation of the interaction of polymerase delta subassemblies with PCNA.
Mammalian DNA polymerase δ (pol δ), a four-subunit enzyme, plays a crucial and versatile role in DNA replication and various DNA repair processes. Its function as a chromosomal DNA polymerase is dependent on the association with proliferating cell nuclear antigen (PCNA) which functions as a molecula...
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Auteurs principaux: | , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/ae2234a9f8a3421ba80d4b5f31efda4a |
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