Comparison of the Efficacy of Dextrose Prolotherapy and Ozone in Patients with Knee Osteoarthritis: A Randomized Cross-Sectional Study

This study aimed to compare the effectiveness of dextrose prolotherapy, ozone therapy, and home exercise programs in patients with knee osteoarthritis. Seventy-five patients with knee osteoarthritis were divided into three groups, with 25 in each group. At week 0 (baseline), week 3, and week 6, 12.5...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Fatih Baygutalp, Mine Çelik, Muhammet Uğur Öztürk, Ahmet Murat Yayık, Ali Ahıskalıoğlu
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	dextrose prolotherapy exercise knee osteoarthritis ozone therapy Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/ae2622f8ff85418c8e6193aa49cf3b94
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ae2622f8ff85418c8e6193aa49cf3b94
record_format	dspace
spelling	oai:doaj.org-article:ae2622f8ff85418c8e6193aa49cf3b942021-11-11T15:04:34ZComparison of the Efficacy of Dextrose Prolotherapy and Ozone in Patients with Knee Osteoarthritis: A Randomized Cross-Sectional Study10.3390/app112199912076-3417https://doaj.org/article/ae2622f8ff85418c8e6193aa49cf3b942021-10-01T00:00:00Zhttps://www.mdpi.com/2076-3417/11/21/9991https://doaj.org/toc/2076-3417This study aimed to compare the effectiveness of dextrose prolotherapy, ozone therapy, and home exercise programs in patients with knee osteoarthritis. Seventy-five patients with knee osteoarthritis were divided into three groups, with 25 in each group. At week 0 (baseline), week 3, and week 6, 12.5% dextrose (intraarticular and periarticular) was administered to the dextrose prolotherapy group. At week 0 (baseline), week 1, and week 2 15 μg/mL ozone (intraarticular and periarticular) was administered to the ozone therapy group. Both groups were also given a home exercise program. The third group was given a home-based exercise therapy program for 12 weeks. All groups were evaluated for VAS, WOMAC, TUG, ROM-active, and ROM-passive values at weeks 0 (baseline), 6, and 12. Ozone therapy more effectively improved VAS scores than dextrose prolotherapy and VAS and WOMAC scores than home-based exercise therapy in the 6th week. Ozone therapy also more effectively improved VAS and WOMAC-stiffness scores than dextrose prolotherapy and VAS, WOMAC, and ROM-active scores than home-based exercise therapy in the 12th week. Both dextrose prolotherapy and ozone therapy are effective in knee osteoarthritis treatment. Ozone therapy should be used in suitable cases rather than dextrose prolotherapy.Fatih BaygutalpMine ÇelikMuhammet Uğur ÖztürkAhmet Murat YayıkAli AhıskalıoğluMDPI AGarticledextrose prolotherapyexercisekneeosteoarthritisozone therapyTechnologyTEngineering (General). Civil engineering (General)TA1-2040Biology (General)QH301-705.5PhysicsQC1-999ChemistryQD1-999ENApplied Sciences, Vol 11, Iss 9991, p 9991 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	dextrose prolotherapy exercise knee osteoarthritis ozone therapy Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999
spellingShingle	dextrose prolotherapy exercise knee osteoarthritis ozone therapy Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999 Fatih Baygutalp Mine Çelik Muhammet Uğur Öztürk Ahmet Murat Yayık Ali Ahıskalıoğlu Comparison of the Efficacy of Dextrose Prolotherapy and Ozone in Patients with Knee Osteoarthritis: A Randomized Cross-Sectional Study
description	This study aimed to compare the effectiveness of dextrose prolotherapy, ozone therapy, and home exercise programs in patients with knee osteoarthritis. Seventy-five patients with knee osteoarthritis were divided into three groups, with 25 in each group. At week 0 (baseline), week 3, and week 6, 12.5% dextrose (intraarticular and periarticular) was administered to the dextrose prolotherapy group. At week 0 (baseline), week 1, and week 2 15 μg/mL ozone (intraarticular and periarticular) was administered to the ozone therapy group. Both groups were also given a home exercise program. The third group was given a home-based exercise therapy program for 12 weeks. All groups were evaluated for VAS, WOMAC, TUG, ROM-active, and ROM-passive values at weeks 0 (baseline), 6, and 12. Ozone therapy more effectively improved VAS scores than dextrose prolotherapy and VAS and WOMAC scores than home-based exercise therapy in the 6th week. Ozone therapy also more effectively improved VAS and WOMAC-stiffness scores than dextrose prolotherapy and VAS, WOMAC, and ROM-active scores than home-based exercise therapy in the 12th week. Both dextrose prolotherapy and ozone therapy are effective in knee osteoarthritis treatment. Ozone therapy should be used in suitable cases rather than dextrose prolotherapy.
format	article
author	Fatih Baygutalp Mine Çelik Muhammet Uğur Öztürk Ahmet Murat Yayık Ali Ahıskalıoğlu
author_facet	Fatih Baygutalp Mine Çelik Muhammet Uğur Öztürk Ahmet Murat Yayık Ali Ahıskalıoğlu
author_sort	Fatih Baygutalp
title	Comparison of the Efficacy of Dextrose Prolotherapy and Ozone in Patients with Knee Osteoarthritis: A Randomized Cross-Sectional Study
title_short	Comparison of the Efficacy of Dextrose Prolotherapy and Ozone in Patients with Knee Osteoarthritis: A Randomized Cross-Sectional Study
title_full	Comparison of the Efficacy of Dextrose Prolotherapy and Ozone in Patients with Knee Osteoarthritis: A Randomized Cross-Sectional Study
title_fullStr	Comparison of the Efficacy of Dextrose Prolotherapy and Ozone in Patients with Knee Osteoarthritis: A Randomized Cross-Sectional Study
title_full_unstemmed	Comparison of the Efficacy of Dextrose Prolotherapy and Ozone in Patients with Knee Osteoarthritis: A Randomized Cross-Sectional Study
title_sort	comparison of the efficacy of dextrose prolotherapy and ozone in patients with knee osteoarthritis: a randomized cross-sectional study
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/ae2622f8ff85418c8e6193aa49cf3b94
work_keys_str_mv	AT fatihbaygutalp comparisonoftheefficacyofdextroseprolotherapyandozoneinpatientswithkneeosteoarthritisarandomizedcrosssectionalstudy AT minecelik comparisonoftheefficacyofdextroseprolotherapyandozoneinpatientswithkneeosteoarthritisarandomizedcrosssectionalstudy AT muhammetugurozturk comparisonoftheefficacyofdextroseprolotherapyandozoneinpatientswithkneeosteoarthritisarandomizedcrosssectionalstudy AT ahmetmuratyayık comparisonoftheefficacyofdextroseprolotherapyandozoneinpatientswithkneeosteoarthritisarandomizedcrosssectionalstudy AT aliahıskalıoglu comparisonoftheefficacyofdextroseprolotherapyandozoneinpatientswithkneeosteoarthritisarandomizedcrosssectionalstudy
_version_	1718437164754141184

Comparison of the Efficacy of Dextrose Prolotherapy and Ozone in Patients with Knee Osteoarthritis: A Randomized Cross-Sectional Study

Ejemplares similares