Simultaneous determination of hydrophilic and lipophilic constituents in herbal medicines using directly-coupled reversed-phase and hydrophilic interaction liquid chromatography-tandem mass spectrometry

Abstract Limitations in the separation ability of conventional liquid chromatography system remains a challenge in developing a versatile method for simultaneously determining both hydrophilic and lipophilic constituents in herbal medicines (HMs). To measure compounds covering a broad polarity span...

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Autores principales: Wan-Yang Sun, Qin-Wei Lu, Hao Gao, Ling Tong, Dong-Xiang Li, Zheng-Qun Zhou, Zheng-Jin Jiang, Henry Sun, Kai-Shun Bi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/ae2b7b82e8d44bfe9e068be662445cf4
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