The impact of cHS4 insulators on DNA transposon vector mobilization and silencing in retinal pigment epithelium cells.

The impact of cHS4 insulators on DNA transposon vector mobilization and silencing in retinal pigment epithelium cells.

DNA transposons have become important vectors for efficient non-viral integration of transgenes into genomic DNA. The Sleeping Beauty (SB), piggyBac (PB), and Tol2 transposable elements have distinct biological properties and currently represent the most promising transposon systems for animal trans...

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Autores principales: Nynne Sharma, Anne Kruse Hollensen, Rasmus O Bak, Nicklas Heine Staunstrup, Lisbeth Dahl Schrøder, Jacob Giehm Mikkelsen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ae30b14198b642d5b0ac2f89ee7ed5d8
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