Paroxetine mitigates cardiac remodelling by doxorubicin and increases survival

Doxorubicin (DOX) is an effective anticancer drug. However, its use is hampered by the development of very mortal cardiomyopathy. Here, we investigate whether the co-administration of the antidepressant paroxetine (P), known to exert beneficial cardiovascular effects, would provide effective cardiop...

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Autores principales: Marija Kosić, Zorica Nešić, Sofija Glumac, Marko Vasić, Vladislav Pajović, Bojana Savić, Nina Japundžić-Žigon
Formato: article
Lenguaje:EN
Publicado: Elsevier 2022
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Acceso en línea:https://doaj.org/article/ae3305f41fc244d78b45f5e1dcb8c74c
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