Prevalence of titanium hypersensitivity in patients with titanium implants: A systematic review and meta-analysis

Background: With increase in exposure to titanium in daily life and its use in medical procedures, there is a greater chance for developing titanium hypersensitivity. Our aim and objective is to examine whether patient patients with titanium implants had a greater incidence of titanium hypersensitiv...

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Autores principales:	Rajsandeep Singh, Gurvanit Lehl, Arshad Bin Hussain, Tejal Nivrutti Abhang, Manisha Mangesh Kulkarni, Mohamed Fadul A Elagib, Rahul V C Tiwari
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	dental implants hypersensitivity metallurgy titanium Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142
Acceso en línea:	https://doaj.org/article/ae3b84208e5b46b6940190c667f360a2
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spelling	oai:doaj.org-article:ae3b84208e5b46b6940190c667f360a22021-11-19T12:15:53ZPrevalence of titanium hypersensitivity in patients with titanium implants: A systematic review and meta-analysis0975-740610.4103/jpbs.jpbs_159_21https://doaj.org/article/ae3b84208e5b46b6940190c667f360a22021-01-01T00:00:00Zhttp://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=6;spage=1345;epage=1349;aulast=Singhhttps://doaj.org/toc/0975-7406Background: With increase in exposure to titanium in daily life and its use in medical procedures, there is a greater chance for developing titanium hypersensitivity. Our aim and objective is to examine whether patient patients with titanium implants had a greater incidence of titanium hypersensitivity or not. Titanium is widely considered to have good biocompatibility. A passivating surface layer of TiO2 is formed when exposed to air which gives it good corrosion resistance. These properties along with its high strength, lightweight, and improvements in smelting technologies have led to its widespread use as an intraosseous and periosteal implant in dentistry and orthopedics. Materials and Methods: Only case–control studies were used for the meta-analysis. Studies with a sample size of <5 were excluded. Cutaneous and epicutaneous tests were used in the study. Results: Three studies met the inclusion criteria. Titanium hypersensitivity is more prevalent in patients with titanium implants. Conclusions: It is also used in a variety of medical devices such as pacemakers and insulin pumps. Moreover, our external exposure to titanium is increasing. It is used in aerospace, chemical, and automobile industries. It is also used in jewelry, home furnishings, and in making sports and marine equipment. Titanium implants increase the possibility of developing titanium hypersensitivity, and thus, it should be considered as a major factor in unexplained implant failure where other causes have been excluded.Rajsandeep SinghGurvanit LehlArshad Bin HussainTejal Nivrutti AbhangManisha Mangesh KulkarniMohamed Fadul A ElagibRahul V C TiwariWolters Kluwer Medknow Publicationsarticledental implantshypersensitivitymetallurgytitaniumPharmacy and materia medicaRS1-441Analytical chemistryQD71-142ENJournal of Pharmacy and Bioallied Sciences, Vol 13, Iss 6, Pp 1345-1349 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	dental implants hypersensitivity metallurgy titanium Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142
spellingShingle	dental implants hypersensitivity metallurgy titanium Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142 Rajsandeep Singh Gurvanit Lehl Arshad Bin Hussain Tejal Nivrutti Abhang Manisha Mangesh Kulkarni Mohamed Fadul A Elagib Rahul V C Tiwari Prevalence of titanium hypersensitivity in patients with titanium implants: A systematic review and meta-analysis
description	Background: With increase in exposure to titanium in daily life and its use in medical procedures, there is a greater chance for developing titanium hypersensitivity. Our aim and objective is to examine whether patient patients with titanium implants had a greater incidence of titanium hypersensitivity or not. Titanium is widely considered to have good biocompatibility. A passivating surface layer of TiO2 is formed when exposed to air which gives it good corrosion resistance. These properties along with its high strength, lightweight, and improvements in smelting technologies have led to its widespread use as an intraosseous and periosteal implant in dentistry and orthopedics. Materials and Methods: Only case–control studies were used for the meta-analysis. Studies with a sample size of <5 were excluded. Cutaneous and epicutaneous tests were used in the study. Results: Three studies met the inclusion criteria. Titanium hypersensitivity is more prevalent in patients with titanium implants. Conclusions: It is also used in a variety of medical devices such as pacemakers and insulin pumps. Moreover, our external exposure to titanium is increasing. It is used in aerospace, chemical, and automobile industries. It is also used in jewelry, home furnishings, and in making sports and marine equipment. Titanium implants increase the possibility of developing titanium hypersensitivity, and thus, it should be considered as a major factor in unexplained implant failure where other causes have been excluded.
format	article
author	Rajsandeep Singh Gurvanit Lehl Arshad Bin Hussain Tejal Nivrutti Abhang Manisha Mangesh Kulkarni Mohamed Fadul A Elagib Rahul V C Tiwari
author_facet	Rajsandeep Singh Gurvanit Lehl Arshad Bin Hussain Tejal Nivrutti Abhang Manisha Mangesh Kulkarni Mohamed Fadul A Elagib Rahul V C Tiwari
author_sort	Rajsandeep Singh
title	Prevalence of titanium hypersensitivity in patients with titanium implants: A systematic review and meta-analysis
title_short	Prevalence of titanium hypersensitivity in patients with titanium implants: A systematic review and meta-analysis
title_full	Prevalence of titanium hypersensitivity in patients with titanium implants: A systematic review and meta-analysis
title_fullStr	Prevalence of titanium hypersensitivity in patients with titanium implants: A systematic review and meta-analysis
title_full_unstemmed	Prevalence of titanium hypersensitivity in patients with titanium implants: A systematic review and meta-analysis
title_sort	prevalence of titanium hypersensitivity in patients with titanium implants: a systematic review and meta-analysis
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/ae3b84208e5b46b6940190c667f360a2
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Prevalence of titanium hypersensitivity in patients with titanium implants: A systematic review and meta-analysis

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