A signal motif retains Arabidopsis ER-α-mannosidase I in the cis-Golgi and prevents enhanced glycoprotein ERAD
The Arabidopsis ER-α-mannosidase I MNS3 generates N-glycan structures typical of ER-resident glycoproteins. Here Schoberer et al. identify a novel motif that anchors MNS3 to the cis-Golgi, spatially separating MNS3 from ER-localized mannose trimming associated with the ER-associated degradation path...
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Nature Portfolio
2019
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oai:doaj.org-article:ae45cf92025043e39d2f6156ceaa447d2021-12-02T14:39:16ZA signal motif retains Arabidopsis ER-α-mannosidase I in the cis-Golgi and prevents enhanced glycoprotein ERAD10.1038/s41467-019-11686-92041-1723https://doaj.org/article/ae45cf92025043e39d2f6156ceaa447d2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11686-9https://doaj.org/toc/2041-1723The Arabidopsis ER-α-mannosidase I MNS3 generates N-glycan structures typical of ER-resident glycoproteins. Here Schoberer et al. identify a novel motif that anchors MNS3 to the cis-Golgi, spatially separating MNS3 from ER-localized mannose trimming associated with the ER-associated degradation pathway.Jennifer SchobererJulia KönigChristiane VeitUlrike VavraEva LiebmingerStanley W. BotchwayFriedrich AltmannVerena KriechbaumerChris HawesRichard StrasserNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
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Science Q Jennifer Schoberer Julia König Christiane Veit Ulrike Vavra Eva Liebminger Stanley W. Botchway Friedrich Altmann Verena Kriechbaumer Chris Hawes Richard Strasser A signal motif retains Arabidopsis ER-α-mannosidase I in the cis-Golgi and prevents enhanced glycoprotein ERAD |
| description |
The Arabidopsis ER-α-mannosidase I MNS3 generates N-glycan structures typical of ER-resident glycoproteins. Here Schoberer et al. identify a novel motif that anchors MNS3 to the cis-Golgi, spatially separating MNS3 from ER-localized mannose trimming associated with the ER-associated degradation pathway. |
| format |
article |
| author |
Jennifer Schoberer Julia König Christiane Veit Ulrike Vavra Eva Liebminger Stanley W. Botchway Friedrich Altmann Verena Kriechbaumer Chris Hawes Richard Strasser |
| author_facet |
Jennifer Schoberer Julia König Christiane Veit Ulrike Vavra Eva Liebminger Stanley W. Botchway Friedrich Altmann Verena Kriechbaumer Chris Hawes Richard Strasser |
| author_sort |
Jennifer Schoberer |
| title |
A signal motif retains Arabidopsis ER-α-mannosidase I in the cis-Golgi and prevents enhanced glycoprotein ERAD |
| title_short |
A signal motif retains Arabidopsis ER-α-mannosidase I in the cis-Golgi and prevents enhanced glycoprotein ERAD |
| title_full |
A signal motif retains Arabidopsis ER-α-mannosidase I in the cis-Golgi and prevents enhanced glycoprotein ERAD |
| title_fullStr |
A signal motif retains Arabidopsis ER-α-mannosidase I in the cis-Golgi and prevents enhanced glycoprotein ERAD |
| title_full_unstemmed |
A signal motif retains Arabidopsis ER-α-mannosidase I in the cis-Golgi and prevents enhanced glycoprotein ERAD |
| title_sort |
signal motif retains arabidopsis er-α-mannosidase i in the cis-golgi and prevents enhanced glycoprotein erad |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/ae45cf92025043e39d2f6156ceaa447d |
| work_keys_str_mv |
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