Decidualisation and placentation defects are a major cause of age-related reproductive decline

Advanced maternal age has been associated with lower reproductive success and higher risk of pregnancy complications. Here the authors show that maternal ageing-related embryonic abnormalities in mouse are caused by decidualisation and placentation defects that can be rescued by transferring the emb...

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Bibliographic Details
Main Authors: Laura Woods, Vicente Perez-Garcia, Jens Kieckbusch, Xiaoqiu Wang, Francesco DeMayo, Francesco Colucci, Myriam Hemberger
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/ae4829e2c1f4498cb0b96e9439f9ed86
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