Spatiotemporal control of coacervate formation within liposomes
The understanding of liquid-liquid phase separation is crucial to cell biology and benefits from cell-mimicking in vitro assays. Here, the authors develop a microfluidic platform to study coacervate formation inside liposomes and show the potential of these hybrid systems to create synthetic cells.
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Nature Portfolio
2019
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oai:doaj.org-article:ae4c34d7c7784f8eba43706f516aa4e92021-12-02T15:35:47ZSpatiotemporal control of coacervate formation within liposomes10.1038/s41467-019-09855-x2041-1723https://doaj.org/article/ae4c34d7c7784f8eba43706f516aa4e92019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09855-xhttps://doaj.org/toc/2041-1723The understanding of liquid-liquid phase separation is crucial to cell biology and benefits from cell-mimicking in vitro assays. Here, the authors develop a microfluidic platform to study coacervate formation inside liposomes and show the potential of these hybrid systems to create synthetic cells.Siddharth DeshpandeFrank BrandenburgAnson LauMart G. F. LastWillem Kasper SpoelstraLouis ReeseSreekar WunnavaMarileen DogteromCees DekkerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
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Science Q Siddharth Deshpande Frank Brandenburg Anson Lau Mart G. F. Last Willem Kasper Spoelstra Louis Reese Sreekar Wunnava Marileen Dogterom Cees Dekker Spatiotemporal control of coacervate formation within liposomes |
| description |
The understanding of liquid-liquid phase separation is crucial to cell biology and benefits from cell-mimicking in vitro assays. Here, the authors develop a microfluidic platform to study coacervate formation inside liposomes and show the potential of these hybrid systems to create synthetic cells. |
| format |
article |
| author |
Siddharth Deshpande Frank Brandenburg Anson Lau Mart G. F. Last Willem Kasper Spoelstra Louis Reese Sreekar Wunnava Marileen Dogterom Cees Dekker |
| author_facet |
Siddharth Deshpande Frank Brandenburg Anson Lau Mart G. F. Last Willem Kasper Spoelstra Louis Reese Sreekar Wunnava Marileen Dogterom Cees Dekker |
| author_sort |
Siddharth Deshpande |
| title |
Spatiotemporal control of coacervate formation within liposomes |
| title_short |
Spatiotemporal control of coacervate formation within liposomes |
| title_full |
Spatiotemporal control of coacervate formation within liposomes |
| title_fullStr |
Spatiotemporal control of coacervate formation within liposomes |
| title_full_unstemmed |
Spatiotemporal control of coacervate formation within liposomes |
| title_sort |
spatiotemporal control of coacervate formation within liposomes |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/ae4c34d7c7784f8eba43706f516aa4e9 |
| work_keys_str_mv |
AT siddharthdeshpande spatiotemporalcontrolofcoacervateformationwithinliposomes AT frankbrandenburg spatiotemporalcontrolofcoacervateformationwithinliposomes AT ansonlau spatiotemporalcontrolofcoacervateformationwithinliposomes AT martgflast spatiotemporalcontrolofcoacervateformationwithinliposomes AT willemkasperspoelstra spatiotemporalcontrolofcoacervateformationwithinliposomes AT louisreese spatiotemporalcontrolofcoacervateformationwithinliposomes AT sreekarwunnava spatiotemporalcontrolofcoacervateformationwithinliposomes AT marileendogterom spatiotemporalcontrolofcoacervateformationwithinliposomes AT ceesdekker spatiotemporalcontrolofcoacervateformationwithinliposomes |
| _version_ |
1718386432822738944 |