Comparison of the fertility of tumor suppressor gene-deficient C57BL/6 mouse strains reveals stable reproductive aging and novel pleiotropic gene

Abstract Tumor suppressor genes are involved in maintaining genome integrity during reproduction (e.g., meiosis). Thus, deleterious alleles in tumor suppressor-deficient mice would exhibit higher mortality during the perinatal period. A recent aging model proposes that perinatal mortality and age-re...

Full description

Saved in:
Bibliographic Details
Main Authors: Masaoki Kohzaki, Akira Ootsuyama, Toshiyuki Umata, Ryuji Okazaki
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/ae51f3e286524bcbacde0b1bd96086a3
Tags: Add Tag
No Tags, Be the first to tag this record!