miR-34a modulates angiotensin II-induced myocardial hypertrophy by direct inhibition of ATG9A expression and autophagic activity.

miR-34a modulates angiotensin II-induced myocardial hypertrophy by direct inhibition of ATG9A expression and autophagic activity.

Cardiac hypertrophy is characterized by thickening myocardium and decreasing in heart chamber volume in response to mechanical or pathological stress, but the underlying molecular mechanisms remain to be defined. This study investigated altered miRNA expression and autophagic activity in pathogenesi...

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Autores principales: Jionghua Huang, Wen Sun, He Huang, Jing Ye, Wei Pan, Yun Zhong, Chuanfang Cheng, Xiangyu You, Benrong Liu, Longgen Xiong, Shiming Liu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ae62eee03c01495eb7c1b9c4af3f2263
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