The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level

The integrity of the stratified epithelia relies on controlled cell turnover but it is unclear how mRNA binding proteins regulates this. Here, the authors show that the RNA binding protein Y-box binding protein-1 translationally represses cytokines, so preventing senescence and maintaining epidermal...

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Autores principales: Eunjeong Kwon, Kristina Todorova, Jun Wang, Rastislav Horos, Kevin K. Lee, Victor A. Neel, Gian Luca Negri, Poul H. Sorensen, Sam W. Lee, Matthias W. Hentze, Anna Mandinova
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/ae77c37590464e83bc58037121dc3a32
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