Promising candidates for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest

Abstract Precise criteria for extracorporeal cardiopulmonary resuscitation (ECPR) are still lacking in patients with out-of-hospital cardiac arrest (OHCA). We aimed to investigate whether adopting our hypothesized criteria for ECPR to patients with refractory OHCA could benefit. This before-after st...

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Autores principales:	Yo Sep Shin, Youn-Jung Kim, Seung Mok Ryoo, Chang Hwan Sohn, Shin Ahn, Dong Woo Seo, Won Young Kim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ae817dafc7a449f1aae59bc20e9f1954
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spelling	oai:doaj.org-article:ae817dafc7a449f1aae59bc20e9f19542021-12-02T13:34:11ZPromising candidates for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest10.1038/s41598-020-79283-12045-2322https://doaj.org/article/ae817dafc7a449f1aae59bc20e9f19542020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-79283-1https://doaj.org/toc/2045-2322Abstract Precise criteria for extracorporeal cardiopulmonary resuscitation (ECPR) are still lacking in patients with out-of-hospital cardiac arrest (OHCA). We aimed to investigate whether adopting our hypothesized criteria for ECPR to patients with refractory OHCA could benefit. This before-after study compared 4.5 years after implementation of ECPR for refractory OHCA patients who met our criteria (Jan, 2015 to May, 2019) and 4 years of undergoing conventional CPR (CCPR) prior to ECPR with patients who met the criteria (Jan, 2011 to Jan, 2014) in the emergency department. The primary and secondary outcomes were good neurologic outcome at 6-months and 1-month respectively, defined as 1 or 2 on the Cerebral Performance Category score. A total of 70 patients (40 with CCPR and 30 with ECPR) were included. For a good neurologic status at 6-months and 1-month, patients with ECPR (33.3%, 26.7%) were superior to those with CCPR (5.0%, 5.0%) (all Ps < 0.05). Among patients with ECPR, a group with a good neurologic status showed shorter low-flow time, longer extracorporeal membrane oxygenation duration and hospital stays, and lower epinephrine doses used (all Ps < 0.05). The application of the detailed indication before initiating ECPR appears to increase a good neurologic outcome rate.Yo Sep ShinYoun-Jung KimSeung Mok RyooChang Hwan SohnShin AhnDong Woo SeoWon Young KimNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yo Sep Shin Youn-Jung Kim Seung Mok Ryoo Chang Hwan Sohn Shin Ahn Dong Woo Seo Won Young Kim Promising candidates for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest
description	Abstract Precise criteria for extracorporeal cardiopulmonary resuscitation (ECPR) are still lacking in patients with out-of-hospital cardiac arrest (OHCA). We aimed to investigate whether adopting our hypothesized criteria for ECPR to patients with refractory OHCA could benefit. This before-after study compared 4.5 years after implementation of ECPR for refractory OHCA patients who met our criteria (Jan, 2015 to May, 2019) and 4 years of undergoing conventional CPR (CCPR) prior to ECPR with patients who met the criteria (Jan, 2011 to Jan, 2014) in the emergency department. The primary and secondary outcomes were good neurologic outcome at 6-months and 1-month respectively, defined as 1 or 2 on the Cerebral Performance Category score. A total of 70 patients (40 with CCPR and 30 with ECPR) were included. For a good neurologic status at 6-months and 1-month, patients with ECPR (33.3%, 26.7%) were superior to those with CCPR (5.0%, 5.0%) (all Ps < 0.05). Among patients with ECPR, a group with a good neurologic status showed shorter low-flow time, longer extracorporeal membrane oxygenation duration and hospital stays, and lower epinephrine doses used (all Ps < 0.05). The application of the detailed indication before initiating ECPR appears to increase a good neurologic outcome rate.
format	article
author	Yo Sep Shin Youn-Jung Kim Seung Mok Ryoo Chang Hwan Sohn Shin Ahn Dong Woo Seo Won Young Kim
author_facet	Yo Sep Shin Youn-Jung Kim Seung Mok Ryoo Chang Hwan Sohn Shin Ahn Dong Woo Seo Won Young Kim
author_sort	Yo Sep Shin
title	Promising candidates for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest
title_short	Promising candidates for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest
title_full	Promising candidates for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest
title_fullStr	Promising candidates for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest
title_full_unstemmed	Promising candidates for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest
title_sort	promising candidates for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/ae817dafc7a449f1aae59bc20e9f1954
work_keys_str_mv	AT yosepshin promisingcandidatesforextracorporealcardiopulmonaryresuscitationforoutofhospitalcardiacarrest AT younjungkim promisingcandidatesforextracorporealcardiopulmonaryresuscitationforoutofhospitalcardiacarrest AT seungmokryoo promisingcandidatesforextracorporealcardiopulmonaryresuscitationforoutofhospitalcardiacarrest AT changhwansohn promisingcandidatesforextracorporealcardiopulmonaryresuscitationforoutofhospitalcardiacarrest AT shinahn promisingcandidatesforextracorporealcardiopulmonaryresuscitationforoutofhospitalcardiacarrest AT dongwooseo promisingcandidatesforextracorporealcardiopulmonaryresuscitationforoutofhospitalcardiacarrest AT wonyoungkim promisingcandidatesforextracorporealcardiopulmonaryresuscitationforoutofhospitalcardiacarrest
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Promising candidates for extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest

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