IIIG9 inhibition in adult ependymal cells changes adherens junctions structure and induces cellular detachment

IIIG9 inhibition in adult ependymal cells changes adherens junctions structure and induces cellular detachment

Abstract Ependymal cells have multiple apical cilia that line the ventricular surfaces and the central canal of spinal cord. In cancer, the loss of ependymal cell polarity promotes the formation of different types of tumors, such as supratentorial anaplastic ependymomas, which are highly aggressive...

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Autores principales: Victor Baeza, Manuel Cifuentes, Fernando Martínez, Eder Ramírez, Francisco Nualart, Luciano Ferrada, María José Oviedo, Isabelle De Lima, Ninoschka Troncoso, Natalia Saldivia, Katterine Salazar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ae82d70191ff4511854dc48d57c6fbe3
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