A dynamical framework for complex fractional killing

Abstract When chemotherapy drugs are applied to tumor cells with the same or similar genotypes, some cells are killed, while others survive. This fractional killing contributes to drug resistance in cancer. Through an incoherent feedforward loop, chemotherapy drugs not only activate p53 to induce ce...

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Auteurs principaux: Richard Ballweg, Andrew L. Paek, Tongli Zhang
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/ae89e0aee4dd4bcc96569fe1115175e6
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