Can we systematically review studies that evaluate complex interventions?

<h4>Background to the debate</h4>The UK Medical Research Council defines complex interventions as those comprising "a number of separate elements which seem essential to the proper functioning of the interventions although the 'active ingredient' of the intervention that i...

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Autores principales:	Sasha Shepperd, Simon Lewin, Sharon Straus, Mike Clarke, Martin P Eccles, Ray Fitzpatrick, Geoff Wong, Aziz Sheikh
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2009
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/ae8e4769d202426b84efd4b37f4ebe63
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spelling	oai:doaj.org-article:ae8e4769d202426b84efd4b37f4ebe632021-12-02T19:55:53ZCan we systematically review studies that evaluate complex interventions?1549-12771549-167610.1371/journal.pmed.1000086https://doaj.org/article/ae8e4769d202426b84efd4b37f4ebe632009-08-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19668360/?tool=EBIhttps://doaj.org/toc/1549-1277https://doaj.org/toc/1549-1676<h4>Background to the debate</h4>The UK Medical Research Council defines complex interventions as those comprising "a number of separate elements which seem essential to the proper functioning of the interventions although the 'active ingredient' of the intervention that is effective is difficult to specify." A typical example is specialist care on a stroke unit, which involves a wide range of health professionals delivering a variety of treatments. Michelle Campbell and colleagues have argued that there are "specific difficulties in defining, developing, documenting, and reproducing complex interventions that are subject to more variation than a drug". These difficulties are one of the reasons why it is challenging for researchers to systematically review complex interventions and synthesize data from separate studies. This PLoS Medicine Debate considers the challenges facing systematic reviewers and suggests several ways of addressing them.Sasha ShepperdSimon LewinSharon StrausMike ClarkeMartin P EcclesRay FitzpatrickGeoff WongAziz SheikhPublic Library of Science (PLoS)articleMedicineRENPLoS Medicine, Vol 6, Iss 8, p e1000086 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R Sasha Shepperd Simon Lewin Sharon Straus Mike Clarke Martin P Eccles Ray Fitzpatrick Geoff Wong Aziz Sheikh Can we systematically review studies that evaluate complex interventions?
description	<h4>Background to the debate</h4>The UK Medical Research Council defines complex interventions as those comprising "a number of separate elements which seem essential to the proper functioning of the interventions although the 'active ingredient' of the intervention that is effective is difficult to specify." A typical example is specialist care on a stroke unit, which involves a wide range of health professionals delivering a variety of treatments. Michelle Campbell and colleagues have argued that there are "specific difficulties in defining, developing, documenting, and reproducing complex interventions that are subject to more variation than a drug". These difficulties are one of the reasons why it is challenging for researchers to systematically review complex interventions and synthesize data from separate studies. This PLoS Medicine Debate considers the challenges facing systematic reviewers and suggests several ways of addressing them.
format	article
author	Sasha Shepperd Simon Lewin Sharon Straus Mike Clarke Martin P Eccles Ray Fitzpatrick Geoff Wong Aziz Sheikh
author_facet	Sasha Shepperd Simon Lewin Sharon Straus Mike Clarke Martin P Eccles Ray Fitzpatrick Geoff Wong Aziz Sheikh
author_sort	Sasha Shepperd
title	Can we systematically review studies that evaluate complex interventions?
title_short	Can we systematically review studies that evaluate complex interventions?
title_full	Can we systematically review studies that evaluate complex interventions?
title_fullStr	Can we systematically review studies that evaluate complex interventions?
title_full_unstemmed	Can we systematically review studies that evaluate complex interventions?
title_sort	can we systematically review studies that evaluate complex interventions?
publisher	Public Library of Science (PLoS)
publishDate	2009
url	https://doaj.org/article/ae8e4769d202426b84efd4b37f4ebe63
work_keys_str_mv	AT sashashepperd canwesystematicallyreviewstudiesthatevaluatecomplexinterventions AT simonlewin canwesystematicallyreviewstudiesthatevaluatecomplexinterventions AT sharonstraus canwesystematicallyreviewstudiesthatevaluatecomplexinterventions AT mikeclarke canwesystematicallyreviewstudiesthatevaluatecomplexinterventions AT martinpeccles canwesystematicallyreviewstudiesthatevaluatecomplexinterventions AT rayfitzpatrick canwesystematicallyreviewstudiesthatevaluatecomplexinterventions AT geoffwong canwesystematicallyreviewstudiesthatevaluatecomplexinterventions AT azizsheikh canwesystematicallyreviewstudiesthatevaluatecomplexinterventions
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Can we systematically review studies that evaluate complex interventions?

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