Recent Advances on Functional Nucleic-Acid Biosensors

In the past few decades, biosensors have been gradually developed for the rapid detection and monitoring of human diseases. Recently, functional nucleic-acid (FNA) biosensors have attracted the attention of scholars due to a series of advantages such as high stability and strong specificity, as well...

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Autores principales:	Xinhong Yu, Shiqi Zhang, Wenqiang Guo, Boxi Li, Yang Yang, Bingqing Xie, Ke Li, Li Zhang
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	biosensor biomedicine functional nucleic acid mediator Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/ae90c096478248a19dc97d5cac5c646d
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spelling	oai:doaj.org-article:ae90c096478248a19dc97d5cac5c646d2021-11-11T19:07:05ZRecent Advances on Functional Nucleic-Acid Biosensors10.3390/s212171091424-8220https://doaj.org/article/ae90c096478248a19dc97d5cac5c646d2021-10-01T00:00:00Zhttps://www.mdpi.com/1424-8220/21/21/7109https://doaj.org/toc/1424-8220In the past few decades, biosensors have been gradually developed for the rapid detection and monitoring of human diseases. Recently, functional nucleic-acid (FNA) biosensors have attracted the attention of scholars due to a series of advantages such as high stability and strong specificity, as well as the significant progress they have made in terms of biomedical applications. However, there are few reports that systematically and comprehensively summarize its working principles, classification and application. In this review, we primarily introduce functional modes of biosensors that combine functional nucleic acids with different signal output modes. In addition, the mechanisms of action of several media of the FNA biosensor are introduced. Finally, the practical application and existing problems of FNA sensors are discussed, and the future development directions and application prospects of functional nucleic acid sensors are prospected.Xinhong YuShiqi ZhangWenqiang GuoBoxi LiYang YangBingqing XieKe LiLi ZhangMDPI AGarticlebiosensorbiomedicinefunctional nucleic acidmediatorChemical technologyTP1-1185ENSensors, Vol 21, Iss 7109, p 7109 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	biosensor biomedicine functional nucleic acid mediator Chemical technology TP1-1185
spellingShingle	biosensor biomedicine functional nucleic acid mediator Chemical technology TP1-1185 Xinhong Yu Shiqi Zhang Wenqiang Guo Boxi Li Yang Yang Bingqing Xie Ke Li Li Zhang Recent Advances on Functional Nucleic-Acid Biosensors
description	In the past few decades, biosensors have been gradually developed for the rapid detection and monitoring of human diseases. Recently, functional nucleic-acid (FNA) biosensors have attracted the attention of scholars due to a series of advantages such as high stability and strong specificity, as well as the significant progress they have made in terms of biomedical applications. However, there are few reports that systematically and comprehensively summarize its working principles, classification and application. In this review, we primarily introduce functional modes of biosensors that combine functional nucleic acids with different signal output modes. In addition, the mechanisms of action of several media of the FNA biosensor are introduced. Finally, the practical application and existing problems of FNA sensors are discussed, and the future development directions and application prospects of functional nucleic acid sensors are prospected.
format	article
author	Xinhong Yu Shiqi Zhang Wenqiang Guo Boxi Li Yang Yang Bingqing Xie Ke Li Li Zhang
author_facet	Xinhong Yu Shiqi Zhang Wenqiang Guo Boxi Li Yang Yang Bingqing Xie Ke Li Li Zhang
author_sort	Xinhong Yu
title	Recent Advances on Functional Nucleic-Acid Biosensors
title_short	Recent Advances on Functional Nucleic-Acid Biosensors
title_full	Recent Advances on Functional Nucleic-Acid Biosensors
title_fullStr	Recent Advances on Functional Nucleic-Acid Biosensors
title_full_unstemmed	Recent Advances on Functional Nucleic-Acid Biosensors
title_sort	recent advances on functional nucleic-acid biosensors
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/ae90c096478248a19dc97d5cac5c646d
work_keys_str_mv	AT xinhongyu recentadvancesonfunctionalnucleicacidbiosensors AT shiqizhang recentadvancesonfunctionalnucleicacidbiosensors AT wenqiangguo recentadvancesonfunctionalnucleicacidbiosensors AT boxili recentadvancesonfunctionalnucleicacidbiosensors AT yangyang recentadvancesonfunctionalnucleicacidbiosensors AT bingqingxie recentadvancesonfunctionalnucleicacidbiosensors AT keli recentadvancesonfunctionalnucleicacidbiosensors AT lizhang recentadvancesonfunctionalnucleicacidbiosensors
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Recent Advances on Functional Nucleic-Acid Biosensors

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