Synergistic insights into human health from aptamer- and antibody-based proteomic profiling

Broad-capture affinity-based proteomic technologies inform how the readout of our genes affects human health. Here, the authors integrate aptamer- and antibody-based profiling to understand the mechanisms underlying gene-protein-disease associations.

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Autores principales: Maik Pietzner, Eleanor Wheeler, Julia Carrasco-Zanini, Nicola D. Kerrison, Erin Oerton, Mine Koprulu, Jian’an Luan, Aroon D. Hingorani, Steve A. Williams, Nicholas J. Wareham, Claudia Langenberg
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ae9a1bfa769147d886496493f0292435
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spelling oai:doaj.org-article:ae9a1bfa769147d886496493f02924352021-11-28T12:33:15ZSynergistic insights into human health from aptamer- and antibody-based proteomic profiling10.1038/s41467-021-27164-02041-1723https://doaj.org/article/ae9a1bfa769147d886496493f02924352021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27164-0https://doaj.org/toc/2041-1723Broad-capture affinity-based proteomic technologies inform how the readout of our genes affects human health. Here, the authors integrate aptamer- and antibody-based profiling to understand the mechanisms underlying gene-protein-disease associations.Maik PietznerEleanor WheelerJulia Carrasco-ZaniniNicola D. KerrisonErin OertonMine KopruluJian’an LuanAroon D. HingoraniSteve A. WilliamsNicholas J. WarehamClaudia LangenbergNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Maik Pietzner
Eleanor Wheeler
Julia Carrasco-Zanini
Nicola D. Kerrison
Erin Oerton
Mine Koprulu
Jian’an Luan
Aroon D. Hingorani
Steve A. Williams
Nicholas J. Wareham
Claudia Langenberg
Synergistic insights into human health from aptamer- and antibody-based proteomic profiling
description Broad-capture affinity-based proteomic technologies inform how the readout of our genes affects human health. Here, the authors integrate aptamer- and antibody-based profiling to understand the mechanisms underlying gene-protein-disease associations.
format article
author Maik Pietzner
Eleanor Wheeler
Julia Carrasco-Zanini
Nicola D. Kerrison
Erin Oerton
Mine Koprulu
Jian’an Luan
Aroon D. Hingorani
Steve A. Williams
Nicholas J. Wareham
Claudia Langenberg
author_facet Maik Pietzner
Eleanor Wheeler
Julia Carrasco-Zanini
Nicola D. Kerrison
Erin Oerton
Mine Koprulu
Jian’an Luan
Aroon D. Hingorani
Steve A. Williams
Nicholas J. Wareham
Claudia Langenberg
author_sort Maik Pietzner
title Synergistic insights into human health from aptamer- and antibody-based proteomic profiling
title_short Synergistic insights into human health from aptamer- and antibody-based proteomic profiling
title_full Synergistic insights into human health from aptamer- and antibody-based proteomic profiling
title_fullStr Synergistic insights into human health from aptamer- and antibody-based proteomic profiling
title_full_unstemmed Synergistic insights into human health from aptamer- and antibody-based proteomic profiling
title_sort synergistic insights into human health from aptamer- and antibody-based proteomic profiling
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/ae9a1bfa769147d886496493f0292435
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