Large scale analysis of phenotype-pathway relationships based on GWAS results.
The widely used pathway-based approach for interpreting Genome Wide Association Studies (GWAS), assumes that since function is executed through the interactions of multiple genes, different perturbations of the same pathway would result in a similar phenotype. This assumption, however, was not syste...
Guardado en:
Autores principales: | Aharon Brodie, Oholi Tovia-Brodie, Yanay Ofran |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ae9e9a719c58409da7081a85b7ae2ea4 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Use of Electrophysiological Studies in Transcatheter Aortic Valve Implantation
por: Oholi Tovia-Brodie, et al.
Publicado: (2020) -
Phenotypic mismatches reveal escape from arms-race coevolution.
por: Charles T Hanifin, et al.
Publicado: (2008) -
Bench Research Informed by GWAS Results
por: Nikolay V. Kondratyev, et al.
Publicado: (2021) -
Qtlizer: comprehensive QTL annotation of GWAS results
por: Matthias Munz, et al.
Publicado: (2020) -
Underestimated effect sizes in GWAS: fundamental limitations of single SNP analysis for dichotomous phenotypes.
por: Sven Stringer, et al.
Publicado: (2011)