Environmental pH modulates inerolysin activity via post-binding blockade

Abstract The cholesterol dependent cytolysins (CDCs) are a family of pore-forming toxins produced by a wide range of bacteria. Some CDCs are important virulence factors for their cognate organisms, but their activity must be tightly regulated to ensure they operate at appropriate times and within th...

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Autores principales: Ryan Rampersaud, Emma L. Lewis, Timothy J. LaRocca, Adam J. Ratner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/aea011bfef974b26a9bb104e9cc10ed8
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