Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review

Yayun Xu,1– 3 Feihu Chen1– 3 1Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, People’s Republic of China; 2The Key Laboratory of Major Autoimmune Diseases of Anhui Province, Anhui Institute of Innovative Drugs, Sch...

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Autores principales:	Xu Y, Chen F
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	antioxidant anti-inflammatory anti-apoptotic nesfatin-1 anorexigenic Pathology RB1-214 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/aea196bd8cbe43ffa013bf5afa510be2
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spelling	oai:doaj.org-article:aea196bd8cbe43ffa013bf5afa510be22021-12-02T10:28:59ZAntioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review1178-7031https://doaj.org/article/aea196bd8cbe43ffa013bf5afa510be22020-09-01T00:00:00Zhttps://www.dovepress.com/antioxidant-anti-inflammatory-and-anti-apoptotic-activities-of-nesfati-peer-reviewed-article-JIRhttps://doaj.org/toc/1178-7031Yayun Xu,1– 3 Feihu Chen1– 3 1Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, People’s Republic of China; 2The Key Laboratory of Major Autoimmune Diseases of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, People’s Republic of China; 3The Key Laboratory of Anti-Inflammatory and Immune Medicines, Ministry of Education, Hefei, People’s Republic of ChinaCorrespondence: Feihu ChenDepartment of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei 230032, People’s Republic of ChinaEmail chenfeihu@ahmu.edu.cnAbstract: Nesfatin-1, a newly identified energy-regulating peptide, is widely expressed in the central and peripheral tissues, and has a variety of physiological activities. A large number of recent studies have shown that nesfatin-1 exhibits antioxidant, anti-inflammatory, and anti-apoptotic properties and is involved in the occurrence and progression of various diseases. This review summarizes current data focusing on the therapeutic effects of nesfatin-1 under different pathophysiological conditions and the mechanisms underlying its antioxidant, anti-inflammatory, and anti-apoptotic activities.Keywords: antioxidant, anti-inflammatory, anti-apoptotic, nesfatin-1, anorexigenicXu YChen FDove Medical Pressarticleantioxidantanti-inflammatoryanti-apoptoticnesfatin-1anorexigenicPathologyRB1-214Therapeutics. PharmacologyRM1-950ENJournal of Inflammation Research, Vol Volume 13, Pp 607-617 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	antioxidant anti-inflammatory anti-apoptotic nesfatin-1 anorexigenic Pathology RB1-214 Therapeutics. Pharmacology RM1-950
spellingShingle	antioxidant anti-inflammatory anti-apoptotic nesfatin-1 anorexigenic Pathology RB1-214 Therapeutics. Pharmacology RM1-950 Xu Y Chen F Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review
description	Yayun Xu,1– 3 Feihu Chen1– 3 1Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, People’s Republic of China; 2The Key Laboratory of Major Autoimmune Diseases of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, People’s Republic of China; 3The Key Laboratory of Anti-Inflammatory and Immune Medicines, Ministry of Education, Hefei, People’s Republic of ChinaCorrespondence: Feihu ChenDepartment of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei 230032, People’s Republic of ChinaEmail chenfeihu@ahmu.edu.cnAbstract: Nesfatin-1, a newly identified energy-regulating peptide, is widely expressed in the central and peripheral tissues, and has a variety of physiological activities. A large number of recent studies have shown that nesfatin-1 exhibits antioxidant, anti-inflammatory, and anti-apoptotic properties and is involved in the occurrence and progression of various diseases. This review summarizes current data focusing on the therapeutic effects of nesfatin-1 under different pathophysiological conditions and the mechanisms underlying its antioxidant, anti-inflammatory, and anti-apoptotic activities.Keywords: antioxidant, anti-inflammatory, anti-apoptotic, nesfatin-1, anorexigenic
format	article
author	Xu Y Chen F
author_facet	Xu Y Chen F
author_sort	Xu Y
title	Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review
title_short	Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review
title_full	Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review
title_fullStr	Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review
title_full_unstemmed	Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review
title_sort	antioxidant, anti-inflammatory and anti-apoptotic activities of nesfatin-1: a review
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/aea196bd8cbe43ffa013bf5afa510be2
work_keys_str_mv	AT xuy antioxidantantiinflammatoryandantiapoptoticactivitiesofnesfatin1areview AT chenf antioxidantantiinflammatoryandantiapoptoticactivitiesofnesfatin1areview
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Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review

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