Compensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control

Perrier et al. examine the neurons of mosquitoes following the development of insecticide resistance-associated point mutations in the voltage-gated sodium channels and AChE1 genes for two resistant strains, KdrKis and AcerKis. Their results show that nAChRs and the intracellular calcium concentrati...

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Autores principales:	Stéphane Perrier, Eléonore Moreau, Caroline Deshayes, Marine El-Adouzi, Delphine Goven, Fabrice Chandre, Bruno Lapied
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/aea29d8dcb42421b88260b19dcc0ba04
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spelling	oai:doaj.org-article:aea29d8dcb42421b88260b19dcc0ba042021-12-02T15:02:48ZCompensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control10.1038/s42003-021-02192-02399-3642https://doaj.org/article/aea29d8dcb42421b88260b19dcc0ba042021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02192-0https://doaj.org/toc/2399-3642Perrier et al. examine the neurons of mosquitoes following the development of insecticide resistance-associated point mutations in the voltage-gated sodium channels and AChE1 genes for two resistant strains, KdrKis and AcerKis. Their results show that nAChRs and the intracellular calcium concentration provide a compensatory mechanism for AcerKis and KdrKis neurons to insecticide exposure.Stéphane PerrierEléonore MoreauCaroline DeshayesMarine El-AdouziDelphine GovenFabrice ChandreBruno LapiedNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Stéphane Perrier Eléonore Moreau Caroline Deshayes Marine El-Adouzi Delphine Goven Fabrice Chandre Bruno Lapied Compensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control
description	Perrier et al. examine the neurons of mosquitoes following the development of insecticide resistance-associated point mutations in the voltage-gated sodium channels and AChE1 genes for two resistant strains, KdrKis and AcerKis. Their results show that nAChRs and the intracellular calcium concentration provide a compensatory mechanism for AcerKis and KdrKis neurons to insecticide exposure.
format	article
author	Stéphane Perrier Eléonore Moreau Caroline Deshayes Marine El-Adouzi Delphine Goven Fabrice Chandre Bruno Lapied
author_facet	Stéphane Perrier Eléonore Moreau Caroline Deshayes Marine El-Adouzi Delphine Goven Fabrice Chandre Bruno Lapied
author_sort	Stéphane Perrier
title	Compensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control
title_short	Compensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control
title_full	Compensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control
title_fullStr	Compensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control
title_full_unstemmed	Compensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control
title_sort	compensatory mechanisms in resistant anopheles gambiae acerkis and kdrkis neurons modulate insecticide-based mosquito control
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/aea29d8dcb42421b88260b19dcc0ba04
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Compensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control

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