QSAR, pharmacophore modeling and molecular docking studies to identify structural alerts for some nitrogen heterocycles as dual inhibitor of telomerase reverse transcriptase and human telomeric G-quadruplex DNA
Abstract Background Telomerase reverse transcriptase (TERT) and human telomeric G-quadruplex DNA are amongst the favorable target for researchers to discover novel and more effective anticancer agents. To understand and elucidate structure activity relationship and mechanism of inhibition of telomer...
Guardado en:
Autores principales: | R. D. Jawarkar, R. L. Bakal, P. N. Khatale, Israa Lewaa, Chetan M. Jain, Jagdish V. Manwar, Minal S. Jaiswal |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
SpringerOpen
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/aea501f2e5bc41f4ae3358eb9f160c10 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
QSAR based virtual screening derived identification of a novel hit as a SARS CoV-229E 3CLpro Inhibitor: GA-MLR QSAR modeling supported by molecular Docking, molecular dynamics simulation and MMGBSA calculation approaches
por: R.D. Jawarkar, et al.
Publicado: (2022) -
SYNTHETIC, SPECTRAL, ANTIMICROBIAL AND QSAR STUDIES ON NOVEL MANNICH BASES OF GLUTARIMIDES
por: DAS MANIKPURI,ANJU, et al.
Publicado: (2010) -
SAR and QSAR in environmental research
Publicado: (1993) -
Semi-automated workflow for molecular pair analysis and QSAR-assisted transformation space expansion
por: Zi-Yi Yang, et al.
Publicado: (2021) -
Azole Compounds as Inhibitors of Candida albicans: QSAR Modelling
por: Davood Gheidari, et al.
Publicado: (2021)