Effect of septal flash on right ventricular systolic function in left bundle-branch block patients with preserved left ventricular ejection fraction

Effect of septal flash on right ventricular systolic function in left bundle-branch block patients with preserved left ventricular ejection fraction

Abstract A leftward motion of the ventricular septum prior to ejection, known as the septal flash (SF), is frequently observed in patients with left bundle-branch block (LBBB). We investigated whether the abnormal motion of the ventricular septum affects right ventricle (RV) contractile performance...

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Autores principales: Guang-yuan Li, Yong-huai Wang, Zheng-yu Guan, Xuan-yi Jin, Yang Li, Shuang Liu, Chun-yan Ma, Jun Yang
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Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/aea6be656e4245c197aae7484bb9642c
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spelling oai:doaj.org-article:aea6be656e4245c197aae7484bb9642c2021-12-02T15:05:59ZEffect of septal flash on right ventricular systolic function in left bundle-branch block patients with preserved left ventricular ejection fraction10.1038/s41598-017-06362-12045-2322https://doaj.org/article/aea6be656e4245c197aae7484bb9642c2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06362-1https://doaj.org/toc/2045-2322Abstract A leftward motion of the ventricular septum prior to ejection, known as the septal flash (SF), is frequently observed in patients with left bundle-branch block (LBBB). We investigated whether the abnormal motion of the ventricular septum affects right ventricle (RV) contractile performance in LBBB patients with preserved left ventricular ejection fraction (LVEF). Forty-four patients with complete LBBB were selected using standard 12-lead electrocardiograms (ECGs), with 30 healthy individuals serving as controls. According to the presence of SF, patients with LBBB were allocated to two subgroups: those with SF (LBBB-SF, n = 24) and those without SF (LBBB-NSF, n = 20). RV longitudinal strain (LS) decreased in LBBB patients with preserved LVEF compared to control subjects (p = 0.002). And RV LS decreased significantly in LBBB-SF patients compared to NSF-LBBB patients (p = 0.04). RV LS correlated negatively with involved septal myocardial segments of SF (r = −0.36, p = 0.02), but did not correlate with the magnitude of SF. RV contractile performance deceased in LBBB patients with preserved LVEF. SF, particularly the extent of this phenomenon, may further affect RV contractile performance.Guang-yuan LiYong-huai WangZheng-yu GuanXuan-yi JinYang LiShuang LiuChun-yan MaJun YangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Guang-yuan Li
Yong-huai Wang
Zheng-yu Guan
Xuan-yi Jin
Yang Li
Shuang Liu
Chun-yan Ma
Jun Yang
Effect of septal flash on right ventricular systolic function in left bundle-branch block patients with preserved left ventricular ejection fraction
description Abstract A leftward motion of the ventricular septum prior to ejection, known as the septal flash (SF), is frequently observed in patients with left bundle-branch block (LBBB). We investigated whether the abnormal motion of the ventricular septum affects right ventricle (RV) contractile performance in LBBB patients with preserved left ventricular ejection fraction (LVEF). Forty-four patients with complete LBBB were selected using standard 12-lead electrocardiograms (ECGs), with 30 healthy individuals serving as controls. According to the presence of SF, patients with LBBB were allocated to two subgroups: those with SF (LBBB-SF, n = 24) and those without SF (LBBB-NSF, n = 20). RV longitudinal strain (LS) decreased in LBBB patients with preserved LVEF compared to control subjects (p = 0.002). And RV LS decreased significantly in LBBB-SF patients compared to NSF-LBBB patients (p = 0.04). RV LS correlated negatively with involved septal myocardial segments of SF (r = −0.36, p = 0.02), but did not correlate with the magnitude of SF. RV contractile performance deceased in LBBB patients with preserved LVEF. SF, particularly the extent of this phenomenon, may further affect RV contractile performance.
format article
author Guang-yuan Li
Yong-huai Wang
Zheng-yu Guan
Xuan-yi Jin
Yang Li
Shuang Liu
Chun-yan Ma
Jun Yang
author_facet Guang-yuan Li
Yong-huai Wang
Zheng-yu Guan
Xuan-yi Jin
Yang Li
Shuang Liu
Chun-yan Ma
Jun Yang
author_sort Guang-yuan Li
title Effect of septal flash on right ventricular systolic function in left bundle-branch block patients with preserved left ventricular ejection fraction
title_short Effect of septal flash on right ventricular systolic function in left bundle-branch block patients with preserved left ventricular ejection fraction
title_full Effect of septal flash on right ventricular systolic function in left bundle-branch block patients with preserved left ventricular ejection fraction
title_fullStr Effect of septal flash on right ventricular systolic function in left bundle-branch block patients with preserved left ventricular ejection fraction
title_full_unstemmed Effect of septal flash on right ventricular systolic function in left bundle-branch block patients with preserved left ventricular ejection fraction
title_sort effect of septal flash on right ventricular systolic function in left bundle-branch block patients with preserved left ventricular ejection fraction
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/aea6be656e4245c197aae7484bb9642c
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