UPF1/SMG7-dependent microRNA-mediated gene regulation

UPF1/SMG7-dependent microRNA-mediated gene regulation

UPF1 mediates the decay of target mRNA in a 3′ untranslated region (UTR)-length-dependent manner. Here the authors reveal that the 3′UTR-length-dependent regulation of UPF1-dependent mRNA decay occurs through EJC-independent but miRNA-dependent regulation.

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Autores principales: Jungyun Park, Jwa-Won Seo, Narae Ahn, Seokju Park, Jungwook Hwang, Jin-Wu Nam
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/aeabc36501bf4d86b4a07be8fc7af2cd
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