Ex vivo confocal microscopy: an emerging technique in dermatology

This review aims to give an overview of the current available applications of ex vivo confocal microscopy (EVCM) in dermatology. EVCM is a relatively new imaging technique that allows microscopic examination of freshly excised unfixed tissue. It enables a rapid examination of the skin sample direct...

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Autores principales:	Elisa Cinotti, Jean Luc Perrot, Bruno Labeille, Frédéric Cambazard, Pietro Rubegni
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2018
Materias:	confocal microscopy dermatology ex vivo fluorescence skin reflectance Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/aeac20d3d9954d56b877515c14031c78
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spelling	oai:doaj.org-article:aeac20d3d9954d56b877515c14031c782021-11-17T08:30:18ZEx vivo confocal microscopy: an emerging technique in dermatology2160-9381https://doaj.org/article/aeac20d3d9954d56b877515c14031c782018-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/352https://doaj.org/toc/2160-9381 This review aims to give an overview of the current available applications of ex vivo confocal microscopy (EVCM) in dermatology. EVCM is a relatively new imaging technique that allows microscopic examination of freshly excised unfixed tissue. It enables a rapid examination of the skin sample directly in the surgery room and thus represents an alternative to the intraoperative micrographic control of the surgical margins of cutaneous tumors by standard microscopic examination on cryopreserved sections during Mohs surgery. Although this technique has mainly been developed for the margin’s control of basal cell carcinoma, many other skin tumors have been studied, including melanoma. Use of EVCM is continuing to evolve, and many possible applications are under investigation, such as the study of nails and hair diseases and the diagnosis of skin infections. Elisa CinottiJean Luc PerrotBruno LabeilleFrédéric CambazardPietro RubegniMattioli1885articleconfocal microscopydermatologyex vivofluorescenceskinreflectanceDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 8, Iss 1 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	confocal microscopy dermatology ex vivo fluorescence skin reflectance Dermatology RL1-803
spellingShingle	confocal microscopy dermatology ex vivo fluorescence skin reflectance Dermatology RL1-803 Elisa Cinotti Jean Luc Perrot Bruno Labeille Frédéric Cambazard Pietro Rubegni Ex vivo confocal microscopy: an emerging technique in dermatology
description	This review aims to give an overview of the current available applications of ex vivo confocal microscopy (EVCM) in dermatology. EVCM is a relatively new imaging technique that allows microscopic examination of freshly excised unfixed tissue. It enables a rapid examination of the skin sample directly in the surgery room and thus represents an alternative to the intraoperative micrographic control of the surgical margins of cutaneous tumors by standard microscopic examination on cryopreserved sections during Mohs surgery. Although this technique has mainly been developed for the margin’s control of basal cell carcinoma, many other skin tumors have been studied, including melanoma. Use of EVCM is continuing to evolve, and many possible applications are under investigation, such as the study of nails and hair diseases and the diagnosis of skin infections.
format	article
author	Elisa Cinotti Jean Luc Perrot Bruno Labeille Frédéric Cambazard Pietro Rubegni
author_facet	Elisa Cinotti Jean Luc Perrot Bruno Labeille Frédéric Cambazard Pietro Rubegni
author_sort	Elisa Cinotti
title	Ex vivo confocal microscopy: an emerging technique in dermatology
title_short	Ex vivo confocal microscopy: an emerging technique in dermatology
title_full	Ex vivo confocal microscopy: an emerging technique in dermatology
title_fullStr	Ex vivo confocal microscopy: an emerging technique in dermatology
title_full_unstemmed	Ex vivo confocal microscopy: an emerging technique in dermatology
title_sort	ex vivo confocal microscopy: an emerging technique in dermatology
publisher	Mattioli1885
publishDate	2018
url	https://doaj.org/article/aeac20d3d9954d56b877515c14031c78
work_keys_str_mv	AT elisacinotti exvivoconfocalmicroscopyanemergingtechniqueindermatology AT jeanlucperrot exvivoconfocalmicroscopyanemergingtechniqueindermatology AT brunolabeille exvivoconfocalmicroscopyanemergingtechniqueindermatology AT fredericcambazard exvivoconfocalmicroscopyanemergingtechniqueindermatology AT pietrorubegni exvivoconfocalmicroscopyanemergingtechniqueindermatology
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Ex vivo confocal microscopy: an emerging technique in dermatology

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