Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma

In gene regulation, diversification at the transcriptome 3′end is linked to differentiation and dedifferentiation. Here, the authors discover extensive transcriptome 3′end-alterations in neuroblastoma, regulated by PCF11, and provide an interactive data repository of transcriptome-wide alternative p...

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Autores principales:	Anton Ogorodnikov, Michal Levin, Surendra Tattikota, Sergey Tokalov, Mainul Hoque, Denise Scherzinger, Federico Marini, Ansgar Poetsch, Harald Binder, Stephan Macher-Göppinger, Hans Christian Probst, Bin Tian, Michael Schaefer, Karl J. Lackner, Frank Westermann, Sven Danckwardt
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aeac44f4a66d4835af5969e60eed4186
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spelling	oai:doaj.org-article:aeac44f4a66d4835af5969e60eed41862021-12-02T14:40:32ZTranscriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma10.1038/s41467-018-07580-52041-1723https://doaj.org/article/aeac44f4a66d4835af5969e60eed41862018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07580-5https://doaj.org/toc/2041-1723In gene regulation, diversification at the transcriptome 3′end is linked to differentiation and dedifferentiation. Here, the authors discover extensive transcriptome 3′end-alterations in neuroblastoma, regulated by PCF11, and provide an interactive data repository of transcriptome-wide alternative polyadenylation.Anton OgorodnikovMichal LevinSurendra TattikotaSergey TokalovMainul HoqueDenise ScherzingerFederico MariniAnsgar PoetschHarald BinderStephan Macher-GöppingerHans Christian ProbstBin TianMichael SchaeferKarl J. LacknerFrank WestermannSven DanckwardtNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anton Ogorodnikov Michal Levin Surendra Tattikota Sergey Tokalov Mainul Hoque Denise Scherzinger Federico Marini Ansgar Poetsch Harald Binder Stephan Macher-Göppinger Hans Christian Probst Bin Tian Michael Schaefer Karl J. Lackner Frank Westermann Sven Danckwardt Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma
description	In gene regulation, diversification at the transcriptome 3′end is linked to differentiation and dedifferentiation. Here, the authors discover extensive transcriptome 3′end-alterations in neuroblastoma, regulated by PCF11, and provide an interactive data repository of transcriptome-wide alternative polyadenylation.
format	article
author	Anton Ogorodnikov Michal Levin Surendra Tattikota Sergey Tokalov Mainul Hoque Denise Scherzinger Federico Marini Ansgar Poetsch Harald Binder Stephan Macher-Göppinger Hans Christian Probst Bin Tian Michael Schaefer Karl J. Lackner Frank Westermann Sven Danckwardt
author_facet	Anton Ogorodnikov Michal Levin Surendra Tattikota Sergey Tokalov Mainul Hoque Denise Scherzinger Federico Marini Ansgar Poetsch Harald Binder Stephan Macher-Göppinger Hans Christian Probst Bin Tian Michael Schaefer Karl J. Lackner Frank Westermann Sven Danckwardt
author_sort	Anton Ogorodnikov
title	Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma
title_short	Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma
title_full	Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma
title_fullStr	Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma
title_full_unstemmed	Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma
title_sort	transcriptome 3′end organization by pcf11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/aeac44f4a66d4835af5969e60eed4186
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Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma

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