Radiation-induced esophagitis in lung cancer

Sarah Baker, Alysa Fairchild Department of Radiation Oncology, Cross Cancer Institute, University of Alberta, Edmonton, AB, Canada Abstract: Radiation-induced esophagitis is the most common local acute toxicity of radiotherapy (RT) delivered for the curative or palliative intent treatment o...

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Autores principales: Baker S, Fairchild A
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2016
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Acceso en línea:https://doaj.org/article/aeb206eaceb9488fb7874f99c22f42a3
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spelling oai:doaj.org-article:aeb206eaceb9488fb7874f99c22f42a32021-12-02T01:37:54ZRadiation-induced esophagitis in lung cancer1179-2728https://doaj.org/article/aeb206eaceb9488fb7874f99c22f42a32016-10-01T00:00:00Zhttps://www.dovepress.com/radiation-induced-esophagitis-in-lung-cancer-peer-reviewed-article-LCTThttps://doaj.org/toc/1179-2728Sarah Baker, Alysa Fairchild Department of Radiation Oncology, Cross Cancer Institute, University of Alberta, Edmonton, AB, Canada Abstract: Radiation-induced esophagitis is the most common local acute toxicity of radiotherapy (RT) delivered for the curative or palliative intent treatment of lung cancer. Although concurrent chemotherapy and higher RT dose are associated with increased esophagitis risk, advancements in RT techniques as well as adherence to esophageal dosimetric constraints may reduce the incidence and severity. Mild acute esophagitis symptoms are generally self-limited, and supportive management options include analgesics, acid suppression, diet modification, treatment for candidiasis, and maintenance of adequate nutrition. Esophageal stricture is the most common late sequela from esophageal irradiation and can be addressed with endoscopic dilatation. Approaches to prevent or mitigate these toxicities are also discussed. Keywords: non–small cell lung cancer, acute, late, toxicity, strictureBaker SFairchild ADove Medical Pressarticleradiationesophagitisnon-small cell lung canceracutelateNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENLung Cancer: Targets and Therapy, Vol Volume 7, Pp 119-127 (2016)
institution DOAJ
collection DOAJ
language EN
topic radiation
esophagitis
non-small cell lung cancer
acute
late
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle radiation
esophagitis
non-small cell lung cancer
acute
late
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Baker S
Fairchild A
Radiation-induced esophagitis in lung cancer
description Sarah Baker, Alysa Fairchild Department of Radiation Oncology, Cross Cancer Institute, University of Alberta, Edmonton, AB, Canada Abstract: Radiation-induced esophagitis is the most common local acute toxicity of radiotherapy (RT) delivered for the curative or palliative intent treatment of lung cancer. Although concurrent chemotherapy and higher RT dose are associated with increased esophagitis risk, advancements in RT techniques as well as adherence to esophageal dosimetric constraints may reduce the incidence and severity. Mild acute esophagitis symptoms are generally self-limited, and supportive management options include analgesics, acid suppression, diet modification, treatment for candidiasis, and maintenance of adequate nutrition. Esophageal stricture is the most common late sequela from esophageal irradiation and can be addressed with endoscopic dilatation. Approaches to prevent or mitigate these toxicities are also discussed. Keywords: non–small cell lung cancer, acute, late, toxicity, stricture
format article
author Baker S
Fairchild A
author_facet Baker S
Fairchild A
author_sort Baker S
title Radiation-induced esophagitis in lung cancer
title_short Radiation-induced esophagitis in lung cancer
title_full Radiation-induced esophagitis in lung cancer
title_fullStr Radiation-induced esophagitis in lung cancer
title_full_unstemmed Radiation-induced esophagitis in lung cancer
title_sort radiation-induced esophagitis in lung cancer
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/aeb206eaceb9488fb7874f99c22f42a3
work_keys_str_mv AT bakers radiationinducedesophagitisinlungcancer
AT fairchilda radiationinducedesophagitisinlungcancer
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