Contributions of histone H3 nucleosome core surface mutations to chromatin structures, silencing and DNA repair.
Histone H3 mutations in residues that cluster in a discrete region on the nucleosome surface around lysine 79 of H3 affect H3-K79 methylation, impair transcriptional silencing in subtelomeric chromatin, and reveal distinct contributions of histone H3 to various DNA-damage response and repair pathway...
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Autores principales: | Michel Fink, Jeffrey S Thompson, Fritz Thoma |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/aebb79bfdcac4cdc856f82c8080ef2c9 |
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