Semi-automatic in silico gap closure enabled de novo assembly of two Dehalobacter genomes from metagenomic data.

Typically, the assembly and closure of a complete bacterial genome requires substantial additional effort spent in a wet lab for gap resolution and genome polishing. Assembly is further confounded by subspecies polymorphism when starting from metagenome sequence data. In this paper, we describe an i...

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Autores principales: Shuiquan Tang, Yunchen Gong, Elizabeth A Edwards
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/aebf233e92b9400992ff53597db26e27
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