A droplet microfluidic platform for high-throughput photochemical reaction discovery

Translating discovery scale vial-based batch reactions to continuous flow scale-up conditions is limited by significant time and resource constraints. Here, the authors report a photochemical droplet microfluidic platform, which enables high throughput reaction discovery in flow to generate pharmace...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Alexandra C. Sun, Daniel J. Steyer, Anthony R. Allen, Emory M. Payne, Robert T. Kennedy, Corey R. J. Stephenson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/aec33517a74540628771a347128e1c41
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:aec33517a74540628771a347128e1c41
record_format dspace
spelling oai:doaj.org-article:aec33517a74540628771a347128e1c412021-12-02T17:32:11ZA droplet microfluidic platform for high-throughput photochemical reaction discovery10.1038/s41467-020-19926-z2041-1723https://doaj.org/article/aec33517a74540628771a347128e1c412020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19926-zhttps://doaj.org/toc/2041-1723Translating discovery scale vial-based batch reactions to continuous flow scale-up conditions is limited by significant time and resource constraints. Here, the authors report a photochemical droplet microfluidic platform, which enables high throughput reaction discovery in flow to generate pharmaceutically relevant compound libraries.Alexandra C. SunDaniel J. SteyerAnthony R. AllenEmory M. PayneRobert T. KennedyCorey R. J. StephensonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alexandra C. Sun
Daniel J. Steyer
Anthony R. Allen
Emory M. Payne
Robert T. Kennedy
Corey R. J. Stephenson
A droplet microfluidic platform for high-throughput photochemical reaction discovery
description Translating discovery scale vial-based batch reactions to continuous flow scale-up conditions is limited by significant time and resource constraints. Here, the authors report a photochemical droplet microfluidic platform, which enables high throughput reaction discovery in flow to generate pharmaceutically relevant compound libraries.
format article
author Alexandra C. Sun
Daniel J. Steyer
Anthony R. Allen
Emory M. Payne
Robert T. Kennedy
Corey R. J. Stephenson
author_facet Alexandra C. Sun
Daniel J. Steyer
Anthony R. Allen
Emory M. Payne
Robert T. Kennedy
Corey R. J. Stephenson
author_sort Alexandra C. Sun
title A droplet microfluidic platform for high-throughput photochemical reaction discovery
title_short A droplet microfluidic platform for high-throughput photochemical reaction discovery
title_full A droplet microfluidic platform for high-throughput photochemical reaction discovery
title_fullStr A droplet microfluidic platform for high-throughput photochemical reaction discovery
title_full_unstemmed A droplet microfluidic platform for high-throughput photochemical reaction discovery
title_sort droplet microfluidic platform for high-throughput photochemical reaction discovery
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/aec33517a74540628771a347128e1c41
work_keys_str_mv AT alexandracsun adropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
AT danieljsteyer adropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
AT anthonyrallen adropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
AT emorympayne adropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
AT roberttkennedy adropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
AT coreyrjstephenson adropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
AT alexandracsun dropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
AT danieljsteyer dropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
AT anthonyrallen dropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
AT emorympayne dropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
AT roberttkennedy dropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
AT coreyrjstephenson dropletmicrofluidicplatformforhighthroughputphotochemicalreactiondiscovery
_version_ 1718380389294145536