Raman microscopy-based quantification of the physical properties of intracellular lipids

Uematsu and Shimizu use Raman spectroscopy to quantify changes in the physical properties of lipid droplets (LDs) and in non-LD cell regions associated with alterations in saturated and unsaturated fatty acid availability in culture medium. Their results suggest that Raman spectroscopy can yield a q...

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Autores principales: Masaaki Uematsu, Takao Shimizu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/aeca55dffeed40f7b806b79128b5fd03
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spelling oai:doaj.org-article:aeca55dffeed40f7b806b79128b5fd032021-12-02T19:16:17ZRaman microscopy-based quantification of the physical properties of intracellular lipids10.1038/s42003-021-02679-w2399-3642https://doaj.org/article/aeca55dffeed40f7b806b79128b5fd032021-10-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02679-whttps://doaj.org/toc/2399-3642Uematsu and Shimizu use Raman spectroscopy to quantify changes in the physical properties of lipid droplets (LDs) and in non-LD cell regions associated with alterations in saturated and unsaturated fatty acid availability in culture medium. Their results suggest that Raman spectroscopy can yield a quantitative measurement of changes in lipid conformation and can quantify trans / gauche ratios in lipid chains.Masaaki UematsuTakao ShimizuNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Masaaki Uematsu
Takao Shimizu
Raman microscopy-based quantification of the physical properties of intracellular lipids
description Uematsu and Shimizu use Raman spectroscopy to quantify changes in the physical properties of lipid droplets (LDs) and in non-LD cell regions associated with alterations in saturated and unsaturated fatty acid availability in culture medium. Their results suggest that Raman spectroscopy can yield a quantitative measurement of changes in lipid conformation and can quantify trans / gauche ratios in lipid chains.
format article
author Masaaki Uematsu
Takao Shimizu
author_facet Masaaki Uematsu
Takao Shimizu
author_sort Masaaki Uematsu
title Raman microscopy-based quantification of the physical properties of intracellular lipids
title_short Raman microscopy-based quantification of the physical properties of intracellular lipids
title_full Raman microscopy-based quantification of the physical properties of intracellular lipids
title_fullStr Raman microscopy-based quantification of the physical properties of intracellular lipids
title_full_unstemmed Raman microscopy-based quantification of the physical properties of intracellular lipids
title_sort raman microscopy-based quantification of the physical properties of intracellular lipids
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/aeca55dffeed40f7b806b79128b5fd03
work_keys_str_mv AT masaakiuematsu ramanmicroscopybasedquantificationofthephysicalpropertiesofintracellularlipids
AT takaoshimizu ramanmicroscopybasedquantificationofthephysicalpropertiesofintracellularlipids
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