Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α

Menopause is associated with metabolic changes and an increased risk of a number of chronic diseases. Here, the authors show in a mouse model of menopause that an amino acid-enriched diet rescues liver lipid metabolism and prevents weight gain in a manner dependent on hepatic ERα.

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Autores principales:	Sara Della Torre, Valeria Benedusi, Giovanna Pepe, Clara Meda, Nicoletta Rizzi, Nina Henriette Uhlenhaut, Adriana Maggi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aecd3a09aeab45749fa1ea641e6e0483
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spelling	oai:doaj.org-article:aecd3a09aeab45749fa1ea641e6e04832021-11-28T12:32:17ZDietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α10.1038/s41467-021-27272-x2041-1723https://doaj.org/article/aecd3a09aeab45749fa1ea641e6e04832021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27272-xhttps://doaj.org/toc/2041-1723Menopause is associated with metabolic changes and an increased risk of a number of chronic diseases. Here, the authors show in a mouse model of menopause that an amino acid-enriched diet rescues liver lipid metabolism and prevents weight gain in a manner dependent on hepatic ERα.Sara Della TorreValeria BenedusiGiovanna PepeClara MedaNicoletta RizziNina Henriette UhlenhautAdriana MaggiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sara Della Torre Valeria Benedusi Giovanna Pepe Clara Meda Nicoletta Rizzi Nina Henriette Uhlenhaut Adriana Maggi Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α
description	Menopause is associated with metabolic changes and an increased risk of a number of chronic diseases. Here, the authors show in a mouse model of menopause that an amino acid-enriched diet rescues liver lipid metabolism and prevents weight gain in a manner dependent on hepatic ERα.
format	article
author	Sara Della Torre Valeria Benedusi Giovanna Pepe Clara Meda Nicoletta Rizzi Nina Henriette Uhlenhaut Adriana Maggi
author_facet	Sara Della Torre Valeria Benedusi Giovanna Pepe Clara Meda Nicoletta Rizzi Nina Henriette Uhlenhaut Adriana Maggi
author_sort	Sara Della Torre
title	Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α
title_short	Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α
title_full	Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α
title_fullStr	Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α
title_full_unstemmed	Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α
title_sort	dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/aecd3a09aeab45749fa1ea641e6e0483
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Dietary essential amino acids restore liver metabolism in ovariectomized mice via hepatic estrogen receptor α

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