Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination

Atropisomers with a chiral C-N axis are useful for natural products synthesis and as ligands in asymmetric catalysis. Here, the authors reportt a π-π interaction and dual H-bond concerted control strategy in enantioselective C-H amination affording configurationally stable N-C atropisomers.

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Autores principales:	He-Yuan Bai, Fu-Xin Tan, Tuan-Qing Liu, Guo-Dong Zhu, Jin-Miao Tian, Tong-Mei Ding, Zhi-Min Chen, Shu-Yu Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aed24a9201da45c9aa481ddd531cd00a
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spelling	oai:doaj.org-article:aed24a9201da45c9aa481ddd531cd00a2021-12-02T16:57:07ZHighly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination10.1038/s41467-019-10858-x2041-1723https://doaj.org/article/aed24a9201da45c9aa481ddd531cd00a2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10858-xhttps://doaj.org/toc/2041-1723Atropisomers with a chiral C-N axis are useful for natural products synthesis and as ligands in asymmetric catalysis. Here, the authors reportt a π-π interaction and dual H-bond concerted control strategy in enantioselective C-H amination affording configurationally stable N-C atropisomers.He-Yuan BaiFu-Xin TanTuan-Qing LiuGuo-Dong ZhuJin-Miao TianTong-Mei DingZhi-Min ChenShu-Yu ZhangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q He-Yuan Bai Fu-Xin Tan Tuan-Qing Liu Guo-Dong Zhu Jin-Miao Tian Tong-Mei Ding Zhi-Min Chen Shu-Yu Zhang Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination
description	Atropisomers with a chiral C-N axis are useful for natural products synthesis and as ligands in asymmetric catalysis. Here, the authors reportt a π-π interaction and dual H-bond concerted control strategy in enantioselective C-H amination affording configurationally stable N-C atropisomers.
format	article
author	He-Yuan Bai Fu-Xin Tan Tuan-Qing Liu Guo-Dong Zhu Jin-Miao Tian Tong-Mei Ding Zhi-Min Chen Shu-Yu Zhang
author_facet	He-Yuan Bai Fu-Xin Tan Tuan-Qing Liu Guo-Dong Zhu Jin-Miao Tian Tong-Mei Ding Zhi-Min Chen Shu-Yu Zhang
author_sort	He-Yuan Bai
title	Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination
title_short	Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination
title_full	Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination
title_fullStr	Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination
title_full_unstemmed	Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination
title_sort	highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine n-c atropisomers through direct enantioselective c-h amination
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/aed24a9201da45c9aa481ddd531cd00a
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Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination

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