Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function
The metabolic regulator protein family, mTOR, regulate natural killer (NK) cell development and function, but the underlying mechanism is unclear. Here, the authors show that Raptor/mTORC1 and Rictor/mTORC2 form a feedback crosstalk network to variegate cytokine and cellular signaling and modulate N...
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Auteurs principaux: | , , , , , , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/aed5a9a2b75b4c99ac71c6c1c1c72f87 |
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