Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections

Polyclonal infections occur when at least two unrelated strains of the same pathogen are detected in an individual. Here, Moreno-Molina et al. analyse sputum and surgical resections from tuberculosis patients, showing that the magnitude of polyclonal infections can be underestimated when only testin...

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Autores principales: Miguel Moreno-Molina, Natalia Shubladze, Iza Khurtsilava, Zaza Avaliani, Nino Bablishvili, Manuela Torres-Puente, Luis Villamayor, Andrei Gabrielian, Alex Rosenthal, Cristina Vilaplana, Sebastien Gagneux, Russell R. Kempker, Sergo Vashakidze, Iñaki Comas
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/aeedd72ae1eb4d95a948ec388691b0ee
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Sumario:Polyclonal infections occur when at least two unrelated strains of the same pathogen are detected in an individual. Here, Moreno-Molina et al. analyse sputum and surgical resections from tuberculosis patients, showing that the magnitude of polyclonal infections can be underestimated when only testing sputum samples.