Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections

Polyclonal infections occur when at least two unrelated strains of the same pathogen are detected in an individual. Here, Moreno-Molina et al. analyse sputum and surgical resections from tuberculosis patients, showing that the magnitude of polyclonal infections can be underestimated when only testin...

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Autores principales:	Miguel Moreno-Molina, Natalia Shubladze, Iza Khurtsilava, Zaza Avaliani, Nino Bablishvili, Manuela Torres-Puente, Luis Villamayor, Andrei Gabrielian, Alex Rosenthal, Cristina Vilaplana, Sebastien Gagneux, Russell R. Kempker, Sergo Vashakidze, Iñaki Comas
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/aeedd72ae1eb4d95a948ec388691b0ee
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spelling	oai:doaj.org-article:aeedd72ae1eb4d95a948ec388691b0ee2021-12-02T14:35:38ZGenomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections10.1038/s41467-021-22705-z2041-1723https://doaj.org/article/aeedd72ae1eb4d95a948ec388691b0ee2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22705-zhttps://doaj.org/toc/2041-1723Polyclonal infections occur when at least two unrelated strains of the same pathogen are detected in an individual. Here, Moreno-Molina et al. analyse sputum and surgical resections from tuberculosis patients, showing that the magnitude of polyclonal infections can be underestimated when only testing sputum samples.Miguel Moreno-MolinaNatalia ShubladzeIza KhurtsilavaZaza AvalianiNino BablishviliManuela Torres-PuenteLuis VillamayorAndrei GabrielianAlex RosenthalCristina VilaplanaSebastien GagneuxRussell R. KempkerSergo VashakidzeIñaki ComasNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Miguel Moreno-Molina Natalia Shubladze Iza Khurtsilava Zaza Avaliani Nino Bablishvili Manuela Torres-Puente Luis Villamayor Andrei Gabrielian Alex Rosenthal Cristina Vilaplana Sebastien Gagneux Russell R. Kempker Sergo Vashakidze Iñaki Comas Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections
description	Polyclonal infections occur when at least two unrelated strains of the same pathogen are detected in an individual. Here, Moreno-Molina et al. analyse sputum and surgical resections from tuberculosis patients, showing that the magnitude of polyclonal infections can be underestimated when only testing sputum samples.
format	article
author	Miguel Moreno-Molina Natalia Shubladze Iza Khurtsilava Zaza Avaliani Nino Bablishvili Manuela Torres-Puente Luis Villamayor Andrei Gabrielian Alex Rosenthal Cristina Vilaplana Sebastien Gagneux Russell R. Kempker Sergo Vashakidze Iñaki Comas
author_facet	Miguel Moreno-Molina Natalia Shubladze Iza Khurtsilava Zaza Avaliani Nino Bablishvili Manuela Torres-Puente Luis Villamayor Andrei Gabrielian Alex Rosenthal Cristina Vilaplana Sebastien Gagneux Russell R. Kempker Sergo Vashakidze Iñaki Comas
author_sort	Miguel Moreno-Molina
title	Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections
title_short	Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections
title_full	Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections
title_fullStr	Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections
title_full_unstemmed	Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections
title_sort	genomic analyses of mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/aeedd72ae1eb4d95a948ec388691b0ee
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Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections

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