Diagnosis of fusion genes using targeted RNA sequencing

Diagnosis of fusion genes using targeted RNA sequencing

Rapid and accurate detection of fusion genes is important in cancer diagnostics. Here, the authors demonstrate that targeted RNA sequencing provides fast, sensitive and quantitative gene fusion detection and overcomes the limitations of approaches currently in clinical use.

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Bibliographic Details
Main Authors: Erin E. Heyer, Ira W. Deveson, Danson Wooi, Christina I. Selinger, Ruth J. Lyons, Vanessa M. Hayes, Sandra A. O’Toole, Mandy L. Ballinger, Devinder Gill, David M. Thomas, Tim R. Mercer, James Blackburn
Format: article
Language:EN
Published: Nature Portfolio 2019
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Science
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Online Access:https://doaj.org/article/aeee7920b057490a96c8d9d9d1354b59
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Summary:Rapid and accurate detection of fusion genes is important in cancer diagnostics. Here, the authors demonstrate that targeted RNA sequencing provides fast, sensitive and quantitative gene fusion detection and overcomes the limitations of approaches currently in clinical use.

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