Rapid insulinotropic action of low doses of bisphenol-A on mouse and human islets of Langerhans: role of estrogen receptor β.

Bisphenol-A (BPA) is a widespread endocrine-disrupting chemical (EDC) used as the base compound in the manufacture of polycarbonate plastics. It alters pancreatic β-cell function and can be considered a risk factor for type 2 diabetes in rodents. Here we used ERβ-/- mice to study whether ERβ is invo...

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Autores principales: Sergi Soriano, Paloma Alonso-Magdalena, Marta García-Arévalo, Anna Novials, Sarheed J Muhammed, Albert Salehi, Jan-Ake Gustafsson, Ivan Quesada, Angel Nadal
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/aeeebe0be17f439882d1e2539c0e31c4
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